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The effects of flutamide on the neonatal rat hypothalamic–pituitary–adrenal and gonadal axes in response to hypoxia

Hypoxia is common with preterm birth and may lead to long‐term effects on the adult hypothalamic–pituitary–adrenal (HPA) axis that are sexually dimorphic due to neonatal androgens. Although the adult rat adrenal does not express appreciable CYP17 activity, the neonatal rat adrenal may synthesize and...

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Detalles Bibliográficos
Autores principales: Rolon, Santiago, Huynh, Christine, Guenther, Maya, Gardezi, Minhal, Phillips, Jonathan, Gehrand, Ashley L., Raff, Hershel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930936/
https://www.ncbi.nlm.nih.gov/pubmed/31876126
http://dx.doi.org/10.14814/phy2.14318