Production of Lentiviral Vectors Using Suspension Cells Grown in Serum-free Media

Lentiviral vectors are increasingly utilized in cell and gene therapy applications because they efficiently transduce target cells such as hematopoietic stem cells and T cells. Large-scale production of current Good Manufacturing Practices-grade lentiviral vectors is limited because of the adherent,...

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Detalles Bibliográficos
Autores principales: Bauler, Matthew, Roberts, Jessica K., Wu, Chang-Chih, Fan, Baochang, Ferrara, Francesca, Yip, Bon Ham, Diao, Shiyong, Kim, Young-In, Moore, Jennifer, Zhou, Sheng, Wielgosz, Matthew M., Ryu, Byoung, Throm, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6931067/
https://www.ncbi.nlm.nih.gov/pubmed/31890741
http://dx.doi.org/10.1016/j.omtm.2019.11.011

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