Inclusion of PF68 Surfactant Improves Stability of rAAV Titer when Passed through a Surgical Device Used in Retinal Gene Therapy

Recent advances in recombinant adeno-associated virus (rAAV) gene therapy for choroideremia show gene replacement to be a promising approach. It is, however, well known that contact of vector solution with plastic materials in the surgical device may result in non-specific adsorption with resulting...

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Detalles Bibliográficos
Autores principales: Patrício, Maria I., Cox, Christopher I., Blue, Clare, Barnard, Alun R., Martinez-Fernandez de la Camara, Cristina, MacLaren, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6931089/
https://www.ncbi.nlm.nih.gov/pubmed/31890744
http://dx.doi.org/10.1016/j.omtm.2019.11.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6931089/
https://www.ncbi.nlm.nih.gov/pubmed/31890744
http://dx.doi.org/10.1016/j.omtm.2019.11.005

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