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Inclusion of PF68 Surfactant Improves Stability of rAAV Titer when Passed through a Surgical Device Used in Retinal Gene Therapy
Recent advances in recombinant adeno-associated virus (rAAV) gene therapy for choroideremia show gene replacement to be a promising approach. It is, however, well known that contact of vector solution with plastic materials in the surgical device may result in non-specific adsorption with resulting...
Autores principales: | Patrício, Maria I., Cox, Christopher I., Blue, Clare, Barnard, Alun R., Martinez-Fernandez de la Camara, Cristina, MacLaren, Robert E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6931089/ https://www.ncbi.nlm.nih.gov/pubmed/31890744 http://dx.doi.org/10.1016/j.omtm.2019.11.005 |
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