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Airway epithelial cell differentiation relies on deficient Hedgehog signalling in COPD
BACKGROUND: Hedgehog (HH) pathway is constantly under scrutiny in the context of organ development. Lung morphogenesis requires HH signalling which participates thereafter to the pulmonary homeostasis by regulating epithelial cell quiescence and repair. Since epithelial remodelling is a hallmark of...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6931110/ https://www.ncbi.nlm.nih.gov/pubmed/31877414 http://dx.doi.org/10.1016/j.ebiom.2019.11.033 |