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The Somatic Mutation Hit on Top of Genetic APC mutations Cause Skin Tumor()

Inactivation of the adenomatous polyposis coli (APC) gene is the initiating event in familial adenomatous polyposis (FAP) patients. Up to 90% of FAP patients show intestinal tumors and other extracolonic malignancies including hepatoblastomas, desmoid tumors, and brain cancer. APC mutation mice (Apc...

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Detalles Bibliográficos
Autores principales:	Niu, Ting, Yang, Mingming, Liu, Qing, Li, Haobin, Jiang, Lingbi, Li, Fanggu, He, Xiaodong, Wang, Lijing, Li, Jiangchao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2019
Materias:	Original article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6931217/ https://www.ncbi.nlm.nih.gov/pubmed/31877462 http://dx.doi.org/10.1016/j.tranon.2019.11.010

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