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Combined Metabolomics and Genome-Wide Transcriptomics Analyses Show Multiple HIF1α-Induced Changes in Lipid Metabolism in Early Stage Clear Cell Renal Cell Carcinoma

The accumulation of lipids is a hallmark of human clear cell renal cell carcinoma (ccRCC). Advanced ccRCC tumors frequently show increased lipid biosynthesis, but the regulation of lipid metabolism in early stage ccRCC tumors has not been studied. Here, we performed combined transcriptomics and meta...

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Detalles Bibliográficos
Autores principales:	van der Mijn, Johannes C., Fu, Leiping, Khani, Francesca, Zhang, Tuo, Molina, Ana M., Barbieri, Christopher E., Chen, Qiuying, Gross, Steven S., Gudas, Lorraine J., Nanus, David M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2019
Materias:	Original article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6931219/ https://www.ncbi.nlm.nih.gov/pubmed/31865180 http://dx.doi.org/10.1016/j.tranon.2019.10.015

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