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The potassium channel KCa3.1 represents a valid pharmacological target for microgliosis-induced neuronal impairment in a mouse model of Parkinson’s disease

BACKGROUND: Recent studies described a critical role for microglia in Parkinson’s disease (PD), where these central nerve system resident immune cells participate in the neuroinflammatory microenvironment that contributes to dopaminergic neurons loss in the substantia nigra. Understanding the phenot...

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Detalles Bibliográficos
Autores principales: Lu, Jia, Dou, Fangfang, Yu, Zhihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6931251/
https://www.ncbi.nlm.nih.gov/pubmed/31878950
http://dx.doi.org/10.1186/s12974-019-1682-2