Novel Quinoline Compound Derivatives of NSC23925 as Potent Reversal Agents Against P-Glycoprotein-Mediated Multidrug Resistance

Multidrug resistance is a serious problem and a common cause of cancer treatment failure, leading to patient death. Although numerous reversal resistance inhibitors have been evaluated in preclinical or clinical trials, efficient and low-toxicity reversal agents have not been identified. In this stu...

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Detalles Bibliográficos
Autores principales: Quan, Xingping, Du, Hongzhi, Xu, Jingjing, Hou, Xiaoying, Gong, Xiaofeng, Wu, Yao, Zhou, Yuqi, Jiang, Jingwei, Lu, Ligong, Yuan, Shengtao, Yang, Xiangyu, Shi, Lei, Sun, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6931887/
https://www.ncbi.nlm.nih.gov/pubmed/31921759
http://dx.doi.org/10.3389/fchem.2019.00820

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