The ETS transcription factor ELF1 regulates a broadly antiviral program distinct from the type I interferon response

Induction of vast transcriptional programs is a central event of innate host responses to viral infections. Here we report a transcriptional program with potent antiviral activity, driven by E74-like ETS transcription factor 1 (ELF1). Using microscopy to quantify viral infection over time, we found...

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Detalles Bibliográficos
Autores principales: Seifert, Leon Louis, Si, Clara, Saha, Debjani, Sadic, Mohammad, de Vries, Maren, Ballentine, Sarah, Briley, Aaron, Wang, Guojun, Valero-Jimenez, Ana M., Mohamed, Adil, Schaefer, Uwe, Moulton, Hong M., García-Sastre, Adolfo, Tripathi, Shashank, Rosenberg, Brad R., Dittmann, Meike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6932815/
https://www.ncbi.nlm.nih.gov/pubmed/31682641
http://dx.doi.org/10.1371/journal.ppat.1007634

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