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A comparative epigenome analysis of gammaherpesviruses suggests cis-acting sequence features as critical mediators of rapid polycomb recruitment

Latent Kaposi sarcoma-associated herpesvirus (KSHV) genomes rapidly acquire distinct patterns of the activating histone modification H3K4-me3 as well as repressive H3K27-me3 marks, a modification linked to transcriptional silencing by polycomb repressive complexes (PRC). Interestingly, PRCs have rec...

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Detalles Bibliográficos
Autores principales:	Günther, Thomas, Fröhlich, Jacqueline, Herrde, Christina, Ohno, Shinji, Burkhardt, Lia, Adler, Heiko, Grundhoff, Adam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6932816/ https://www.ncbi.nlm.nih.gov/pubmed/31671162 http://dx.doi.org/10.1371/journal.ppat.1007838

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