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Absence of a synergic nigral proapoptotic effect triggered by REM sleep deprivation in the rotenone model of Parkinson´s disease

Excitotoxicity has been related to play a crucial role in Parkinson's disease (PD) pathogenesis. Pedunculopontine tegmental nucleus (PPT) represents one of the major sources of glutamatergic afferences to nigrostriatal pathway and putative reciprocal connectivity between these structures may ex...

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Detalles Bibliográficos
Autores principales: Kmita, Luana C, Ilkiw, Jessica L, Rodrigues, Lais S, Targa, Adriano DS, Noseda, Ana Carolina D, dos-Santos, Patrícia, Fagotti, Juliane, Trindade, Edvaldo S., Lima, Marcelo MS
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Brazilian Association of Sleep and Latin American Federation of Sleep 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6932851/
https://www.ncbi.nlm.nih.gov/pubmed/31890096
http://dx.doi.org/10.5935/1984-0063.20190078