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Absence of a synergic nigral proapoptotic effect triggered by REM sleep deprivation in the rotenone model of Parkinson´s disease
Excitotoxicity has been related to play a crucial role in Parkinson's disease (PD) pathogenesis. Pedunculopontine tegmental nucleus (PPT) represents one of the major sources of glutamatergic afferences to nigrostriatal pathway and putative reciprocal connectivity between these structures may ex...
Autores principales: | Kmita, Luana C, Ilkiw, Jessica L, Rodrigues, Lais S, Targa, Adriano DS, Noseda, Ana Carolina D, dos-Santos, Patrícia, Fagotti, Juliane, Trindade, Edvaldo S., Lima, Marcelo MS |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Brazilian Association of Sleep and Latin American Federation of Sleep
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6932851/ https://www.ncbi.nlm.nih.gov/pubmed/31890096 http://dx.doi.org/10.5935/1984-0063.20190078 |
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