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Morphine Differentially Alters the Synaptic and Intrinsic Properties of D1R- and D2R-Expressing Medium Spiny Neurons in the Nucleus Accumbens

Exposure to opioids reshapes future reward and motivated behaviors partially by altering the functional output of medium spiny neurons (MSNs) in the nucleus accumbens shell. Here, we investigated how morphine, a highly addictive opioid, alters synaptic transmission and intrinsic excitability on dopa...

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Detalles Bibliográficos
Autores principales:	McDevitt, Dillon S., Jonik, Benjamin, Graziane, Nicholas M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6932971/ https://www.ncbi.nlm.nih.gov/pubmed/31920618 http://dx.doi.org/10.3389/fnsyn.2019.00035

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