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Treatment With 2-BFI Attenuated Spinal Cord Injury by Inhibiting Oxidative Stress and Neuronal Apoptosis via the Nrf2 Signaling Pathway
Previous reports showed that 2-(-2-benzofuranyl)-2-imidazoline (2-BFI) has antioxidant, anti-inflammatory and anti-apoptotic effects on neuroprotection in numerous disorders. However, the precise mechanisms remain elusive. The nuclear factor c factor 2 (Nrf2)/antioxidant response element (ARE) signa...
Autores principales: | Lin, Xiaolong, Zhu, Jie, Ni, Haibo, Rui, Qin, Sha, Weiping, Yang, Huilin, Li, Di, Chen, Gang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6932985/ https://www.ncbi.nlm.nih.gov/pubmed/31920564 http://dx.doi.org/10.3389/fncel.2019.00567 |
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