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Nitric oxide, DPPH and hydrogen peroxide radical scavenging activity of TEMPO terminated polyurethane dendrimers: Data supporting antioxidant activity of radical dendrimers

This article describes free radical scavenging activity of TEMPO (2, 2, 6, 6-tetramethylpiperidin-1-yloxyl) radical functionalized dendrimers of generation G0 - G4 against nitric oxide (NO), 1, 1-diphenyl-2-picrylhydrazyl (DPPH) and hydrogen peroxide (H(2)O(2)) radicals. The total antioxidant activi...

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Autores principales: Ali, Badusha Mohamad, Boothapandi, Madakkannu, Sultan Nasar, AbdulSalam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933143/
https://www.ncbi.nlm.nih.gov/pubmed/31890810
http://dx.doi.org/10.1016/j.dib.2019.104972
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author Ali, Badusha Mohamad
Boothapandi, Madakkannu
Sultan Nasar, AbdulSalam
author_facet Ali, Badusha Mohamad
Boothapandi, Madakkannu
Sultan Nasar, AbdulSalam
author_sort Ali, Badusha Mohamad
collection PubMed
description This article describes free radical scavenging activity of TEMPO (2, 2, 6, 6-tetramethylpiperidin-1-yloxyl) radical functionalized dendrimers of generation G0 - G4 against nitric oxide (NO), 1, 1-diphenyl-2-picrylhydrazyl (DPPH) and hydrogen peroxide (H(2)O(2)) radicals. The total antioxidant activity of the dendrimers was also reported and compared with pure 4-hydoxy TEMPO (constituent of dendrimers) and ascorbic acid (vitamin C) standard. The activity of TEMPO functionalized G4 dendrimer against scavenging of nitric oxide and hydrogen peroxide radicals was found comparable to vitamin C. The data presented in this article supports the good antioxidant activity of the dendrimers newly reported in our previous publication (Radical dendrimers: Synthesis, anti-tumor activity and enhanced cytoprotective performance of TEMPO free radical functionalized polyurethane dendrimers).
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spelling pubmed-69331432019-12-30 Nitric oxide, DPPH and hydrogen peroxide radical scavenging activity of TEMPO terminated polyurethane dendrimers: Data supporting antioxidant activity of radical dendrimers Ali, Badusha Mohamad Boothapandi, Madakkannu Sultan Nasar, AbdulSalam Data Brief Materials Science This article describes free radical scavenging activity of TEMPO (2, 2, 6, 6-tetramethylpiperidin-1-yloxyl) radical functionalized dendrimers of generation G0 - G4 against nitric oxide (NO), 1, 1-diphenyl-2-picrylhydrazyl (DPPH) and hydrogen peroxide (H(2)O(2)) radicals. The total antioxidant activity of the dendrimers was also reported and compared with pure 4-hydoxy TEMPO (constituent of dendrimers) and ascorbic acid (vitamin C) standard. The activity of TEMPO functionalized G4 dendrimer against scavenging of nitric oxide and hydrogen peroxide radicals was found comparable to vitamin C. The data presented in this article supports the good antioxidant activity of the dendrimers newly reported in our previous publication (Radical dendrimers: Synthesis, anti-tumor activity and enhanced cytoprotective performance of TEMPO free radical functionalized polyurethane dendrimers). Elsevier 2019-12-11 /pmc/articles/PMC6933143/ /pubmed/31890810 http://dx.doi.org/10.1016/j.dib.2019.104972 Text en © 2019 Published by Elsevier Inc. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Materials Science
Ali, Badusha Mohamad
Boothapandi, Madakkannu
Sultan Nasar, AbdulSalam
Nitric oxide, DPPH and hydrogen peroxide radical scavenging activity of TEMPO terminated polyurethane dendrimers: Data supporting antioxidant activity of radical dendrimers
title Nitric oxide, DPPH and hydrogen peroxide radical scavenging activity of TEMPO terminated polyurethane dendrimers: Data supporting antioxidant activity of radical dendrimers
title_full Nitric oxide, DPPH and hydrogen peroxide radical scavenging activity of TEMPO terminated polyurethane dendrimers: Data supporting antioxidant activity of radical dendrimers
title_fullStr Nitric oxide, DPPH and hydrogen peroxide radical scavenging activity of TEMPO terminated polyurethane dendrimers: Data supporting antioxidant activity of radical dendrimers
title_full_unstemmed Nitric oxide, DPPH and hydrogen peroxide radical scavenging activity of TEMPO terminated polyurethane dendrimers: Data supporting antioxidant activity of radical dendrimers
title_short Nitric oxide, DPPH and hydrogen peroxide radical scavenging activity of TEMPO terminated polyurethane dendrimers: Data supporting antioxidant activity of radical dendrimers
title_sort nitric oxide, dpph and hydrogen peroxide radical scavenging activity of tempo terminated polyurethane dendrimers: data supporting antioxidant activity of radical dendrimers
topic Materials Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933143/
https://www.ncbi.nlm.nih.gov/pubmed/31890810
http://dx.doi.org/10.1016/j.dib.2019.104972
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