Cargando…
Noise-induced loss of sensory hair cells is mediated by ROS/AMPKα pathway
The formation of reactive oxygen species (ROS) is a well-documented process in noise-induced hearing loss (NIHL). We have also previously shown that activation of 5’ adenosine monophosphate (AMP)-activated protein kinase (AMPKα) at its catalytic residue T172 is one of the key reactions triggering no...
Autores principales: | Wu, Fan, Xiong, Hao, Sha, Suhua |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933152/ https://www.ncbi.nlm.nih.gov/pubmed/31926629 http://dx.doi.org/10.1016/j.redox.2019.101406 |
Ejemplares similares
-
Mitochondrial Calcium Transporters Mediate Sensitivity to Noise-Induced Losses of Hair Cells and Cochlear Synapses
por: Wang, Xianren, et al.
Publicado: (2019) -
Accumulated ROS Activates HIF-1α-Induced Glycolysis and Exerts a Protective Effect on Sensory Hair Cells Against Noise-Induced Damage
por: Liang, Shuo, et al.
Publicado: (2022) -
Receptor-interacting protein kinases modulate noise-induced sensory hair cell death
por: Zheng, H-W, et al.
Publicado: (2014) -
CFTR potentiator ivacaftor protects against noise-induced hair cell loss by increasing Nrf2 and reducing oxidative stress
por: Wu, Fan, et al.
Publicado: (2023) -
ERK2 mediates inner hair cell survival and decreases susceptibility to noise-induced hearing loss
por: Kurioka, Takaomi, et al.
Publicado: (2015)