Phase III, placebo-controlled, randomized, double-blind trial of tableted, therapeutic TB vaccine (V7) containing heat-killed M. vaccae administered daily for one month

OBJECTIVE: Immunotherapy of tuberculosis (TB) to shorten treatment duration represents an unmet medical need. Orally delivered, tableted TB vaccine (V7) containing heat-killed Mycobacterium vaccae (NCTC 11659) has been demonstrated in prior clinical studies to be safe and fast-acting immune adjunct....

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Detalles Bibliográficos
Autores principales: Bourinbaiar, Aldar S., Batbold, Uyanga, Efremenko, Yuri, Sanjagdorj, Munkhburam, Butov, Dmytro, Damdinpurev, Narantsetseg, Grinishina, Elena, Mijiddorj, Otgonbayar, Kovolev, Mikola, Baasanjav, Khaliunaa, Butova, Tetyana, Prihoda, Natalia, Batbold, Ochirbat, Yurchenko, Larisa, Tseveendorj, Ariungerel, Arzhanova, Olga, Chunt, Erkhemtsetseg, Stepanenko, Hanna, Sokolenko, Nina, Makeeva, Natalia, Tarakanovskaya, Marina, Borisova, Vika, Reid, Alan, Kalashnikov, Valeryi, Nyasulu, Peter, Prabowo, Satria A., Jirathitikal, Vichai, Bain, Allen I., Stanford, Cynthia, Stanford, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933248/
https://www.ncbi.nlm.nih.gov/pubmed/31890902
http://dx.doi.org/10.1016/j.jctube.2019.100141

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