Cargando…

CYP2J2/EET reduces vulnerability to atrial fibrillation in chronic pressure overload mice

Growing evidence has well established the protective effects of CYP2J2/EET on the cardiovascular system. The aim of the present study was to determine whether CYP2J2/EET has a preventive effect on atrial fibrillation (AF) and to investigate the underlying mechanisms. Wild‐type mice were injected wit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Xuguang, Zhu, Feng, Meng, Weidong, Zhang, Feng, Hong, Jiang, Zhang, Guobing, Wang, Fang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933320/ https://www.ncbi.nlm.nih.gov/pubmed/31749335 http://dx.doi.org/10.1111/jcmm.14796

Ejemplares similares

Regulation of CYP2J2 and EET Levels in Cardiac Disease and Diabetes
por: Aliwarga, Theresa, et al.
Publicado: (2018)

Inducible CYP2J2 and Its Product 11,12-EET Promotes Bacterial Phagocytosis: A Role for CYP2J2 Deficiency in the Pathogenesis of Crohn’s Disease?
por: Bystrom, Jonas, et al.
Publicado: (2013)

CYP2J2 and Its Metabolites EETs Attenuate Insulin Resistance via Regulating Macrophage Polarization in Adipose Tissue
por: Dai, Meiyan, et al.
Publicado: (2017)

CYP2J2 and EETs protect against pulmonary arterial hypertension with lung ischemia–reperfusion injury in vivo and in vitro
por: Ding, Yun, et al.
Publicado: (2021)

Sex differences in blood pressure control in SHR: lack of a role for EETs
por: Moulana, Mohadetheh, et al.
Publicado: (2014)

Sacubitril/Valsartan Improves Left Atrial and Left Atrial Appendage Function in Patients With Atrial Fibrillation and in Pressure Overload-Induced Mice
por: Suo, Ya, et al.
Publicado: (2019)

2nd International Conference on Education and Educational Technology (EET 2011)
por: Wang, Yuanzhi
Publicado: (2012)

2nd International Conference on Education and Educational Technology (EET 2011)
por: Wang, Yuanzhi
Publicado: (2012)

Aging, Estrogen Loss and Epoxyeicosatrienoic Acids (EETs)
por: Lee, Alison R., et al.
Publicado: (2013)

“NETs and EETs, a Whole Web of Mess”
por: Williams, Tyler L., et al.
Publicado: (2020)

The development of novel cytochrome P450 2J2 (CYP2J2) inhibitor and the underlying interaction between inhibitor and CYP2J2
por: Tian, Xiangge, et al.
Publicado: (2021)

The Contribution of Arachidonic Acid Metabolites EETs to Inflammation in Obesity
por: Mashayekhi, Mona, et al.
Publicado: (2021)

Sexually Dimorphic Regulation of EET Synthesis and Metabolism: Roles of Estrogen
por: Huang, An, et al.
Publicado: (2018)

Metformin regulates adiponectin signalling in epicardial adipose tissue and reduces atrial fibrillation vulnerability
por: Li, Biao, et al.
Publicado: (2020)

Left atrial effective conducting size predicts atrial fibrillation vulnerability in persistent but not paroxysmal atrial fibrillation
por: Williams, Steven E., et al.
Publicado: (2019)

20-HETE and EETs in Diabetic Nephropathy: A Novel Mechanistic Pathway
por: Eid, Stephanie, et al.
Publicado: (2013)

Theoretical model for neurovascular coupling via interactions of NO, EET, and 20-HETE
por: Kang, Hyuk, et al.
Publicado: (2013)

14,15-EET induces the infiltration and tumor-promoting function of neutrophils to trigger the growth of minimal dormant metastases
por: Luo, Jing, et al.
Publicado: (2016)

14,15-EET Reduced Brain Injury from Cerebral Ischemia and Reperfusion via Suppressing Neuronal Parthanatos
por: Zhao, Haipeng, et al.
Publicado: (2021)

PU.1 inhibition attenuates atrial fibrosis and atrial fibrillation vulnerability induced by angiotensin‐II by reducing TGF‐β1/Smads pathway activation
por: Hu, Juan, et al.
Publicado: (2021)

Epoxyeicosatrienoic Acid Analog EET-A Blunts Development of Lupus Nephritis in Mice
por: Hye Khan, Md. Abdul, et al.
Publicado: (2019)

Kidney-Targeted Epoxyeicosatrienoic Acid Analog, EET-F01, Reduces Inflammation, Oxidative Stress, and Cisplatin-Induced Nephrotoxicity
por: Imig, John D., et al.
Publicado: (2021)

Hydrogen-rich saline mitigates pressure overload-induced cardiac hypertrophy and atrial fibrillation in rats via the JAK-STAT signalling pathway
por: Wang, Chufeng, et al.
Publicado: (2020)

EETs/sEHi alleviates nociception by blocking the crosslink between endoplasmic reticulum stress and neuroinflammation in a central poststroke pain model
por: Liu, Tongtong, et al.
Publicado: (2021)

Hyperhomocysteinemia results from and promotes hepatocellular carcinoma via CYP450 metabolism by CYP2J2 DNA methylation
por: Zhang, Donghong, et al.
Publicado: (2016)

EETs reduces LPS-induced hyperpermeability by targeting GRP78 mediated Src activation and subsequent Rho/ROCK signaling pathway
por: Dong, Ruolan, et al.
Publicado: (2017)

Role of Cyp2j6 in Brown Adipogenesis
por: Zhao, Ling, et al.
Publicado: (2022)

Polymorphisms of CYP2C9*2, CYP2C9*3 and VKORC1 genes related to time in therapeutic range in patients with atrial fibrillation using warfarin
por: da Silveira, Maria Mariana Barros Melo, et al.
Publicado: (2019)

Diltiazem efficacy and CYP2D6 gene polymorphism in patients with atrial fibrillation with rapid ventricular response
por: Uluturk, Mehmet, et al.
Publicado: (2023)

Doxycycline Improves Fibrosis-Induced Abnormalities in Atrial Conduction and Vulnerability to Atrial Fibrillation in Chronic Intermittent Hypoxia Rats
por: Ma, Zuowang, et al.
Publicado: (2020)

CYP11B2 T-344C Gene Polymorphism and Atrial Fibrillation: A Meta-Analysis of 2,758 Subjects
por: Li, Yan-yan, et al.
Publicado: (2012)

Effects of different CYP2C19 genotypes on prognosis of patients complicated with atrial fibrillation taking clopidogrel after PCI
por: Zhang, Qifeng, et al.
Publicado: (2018)

PPARγ signaling is required for mediating EETs protective effects in neonatal cardiomyocytes exposed to LPS
por: Samokhvalov, Victor, et al.
Publicado: (2014)

Impact of effective refractory period personalization on prediction of atrial fibrillation vulnerability
por: Martinez Diaz, P, et al.
Publicado: (2023)

EETs alleviate alveolar epithelial cell senescence by inhibiting endoplasmic reticulum stress through the Trim25/Keap1/Nrf2 axis
por: Zhang, Chen-Yu, et al.
Publicado: (2023)

In vitro and In silico studies of interactions of cathinone with human recombinant cytochrome P450 CYP(1A2), CYP2A6, CYP2B6, CYP2C8, CYP2C19, CYP2E1, CYP2J2, and CYP3A5
por: Lim, Sharoen Yu Ming, et al.
Publicado: (2022)

Masking of Pressure Overload in a Patient with Pulmonary Thromboembolism Accompanied by Atrial Septal Aneurysm
por: Yu, Tae Kyung, et al.
Publicado: (2011)

Vascular endothelial overexpression of human CYP2J2 (Tie2-CYP2J2 Tr) modulates cardiac oxylipin profiles and enhances coronary reactive hyperemia in mice
por: Hanif, Ahmad, et al.
Publicado: (2017)

Edaravone inhibits pressure overload-induced cardiac fibrosis and dysfunction by reducing expression of angiotensin II AT1 receptor
por: Zhang, Wei-Wei, et al.
Publicado: (2017)

Leukocytic Toll-Like Receptor 2 Deficiency Preserves Cardiac Function And Reduces Fibrosis In Sustained Pressure Overload
por: Wang, Jiong-Wei, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_c7iujjlt6s91gr5ij8het9pep3