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Manganese activates autophagy to alleviate endoplasmic reticulum stress–induced apoptosis via PERK pathway

Overexposure to manganese (Mn) is neurotoxic. Our previous research has demonstrated that the interaction of endoplasmic reticulum (ER) stress and autophagy participates in the early stage of Mn‐mediated neurotoxicity in mouse. However, the mechanisms of ER stress signalling pathways in the initiati...

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Detalles Bibliográficos
Autores principales: Liu, Chang, Yan, Dong‐Ying, Wang, Can, Ma, Zhuo, Deng, Yu, Liu, Wei, Xu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933331/
https://www.ncbi.nlm.nih.gov/pubmed/31639278
http://dx.doi.org/10.1111/jcmm.14732