Cargando…
Down‐regulation of the mitochondrial i‐AAA protease Yme1L induces muscle atrophy via FoxO3a and myostatin activation
Muscle atrophy is closely associated with many diseases, including diabetes and cardiac failure. Growing evidence has shown that mitochondrial dysfunction is related to muscle atrophy; however, the underlying mechanisms are still unclear. To elucidate how mitochondrial dysfunction causes muscle atro...
Autores principales: | Lee, Yoo Jeong, Kim, Gyu Hee, Park, Sang Ick, Lim, Joo Hyun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933342/ https://www.ncbi.nlm.nih.gov/pubmed/31725201 http://dx.doi.org/10.1111/jcmm.14799 |
Ejemplares similares
-
Role of the AAA protease Yme1 in folding of proteins in the intermembrane space of mitochondria
por: Schreiner, Bernadette, et al.
Publicado: (2012) -
Loss of the mitochondrial i‐AAA protease YME1L leads to ocular dysfunction and spinal axonopathy
por: Sprenger, Hans‐Georg, et al.
Publicado: (2018) -
Metformin induces muscle atrophy by transcriptional regulation of myostatin via HDAC6 and FoxO3a
por: Kang, Min Ju, et al.
Publicado: (2021) -
The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission
por: Anand, Ruchika, et al.
Publicado: (2014) -
Loss of Mitochondrial AAA Proteases AFG3L2 and YME1L Impairs Mitochondrial Structure and Respiratory Chain Biogenesis
por: Cesnekova, Jana, et al.
Publicado: (2018)