Oridonin prevents insulin resistance–mediated cognitive disorder through PTEN/Akt pathway and autophagy in minimal hepatic encephalopathy

Minimal hepatic encephalopathy (MHE) was characterized for cognitive dysfunction. Insulin resistance (IR) has been identified to be correlated with the pathogenesis of MHE. Oridonin (Ori) is an active terpenoid, which has been reported to rescue synaptic loss and restore insulin sensitivity. In this...

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Detalles Bibliográficos
Autores principales: Wen, Fangfang, Zhuge, Weishan, Wang, Jian, Lu, Xiaoai, You, Ruimin, Liu, Leping, Zhuge, Qichuan, Ding, Saidan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933371/
https://www.ncbi.nlm.nih.gov/pubmed/31568638
http://dx.doi.org/10.1111/jcmm.14546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933371/
https://www.ncbi.nlm.nih.gov/pubmed/31568638
http://dx.doi.org/10.1111/jcmm.14546

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