Cargando…

Inhibition of miR‐21 alleviated cardiac perivascular fibrosis via repressing EndMT in T1DM

In type 1 and type 2 diabetes mellitus, increased cardiac fibrosis, stiffness and associated diastolic dysfunction may be the earliest pathological phenomena in diabetic cardiomyopathy. Endothelial‐mesenchymal transition (EndMT) in endothelia cells (ECs) is a critical cellular phenomenon that increa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Qianqian, Yao, Yufeng, Shi, Shumei, Zhou, Mengchen, Zhou, Yingchao, Wang, Mengru, Chiu, Jeng‐Jiann, Huang, Zhengrong, Zhang, Weili, Liu, Min, Wang, Qing, Tu, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933373/ https://www.ncbi.nlm.nih.gov/pubmed/31680453 http://dx.doi.org/10.1111/jcmm.14800

Ejemplares similares

Knockout RAGE alleviates cardiac fibrosis through repressing endothelial-to-mesenchymal transition (EndMT) mediated by autophagy
por: Zhang, Lu, et al.
Publicado: (2021)

To be EndMT or not to be, that is the question in pulmonary hypertension
por: Xiong, Jianhua
Publicado: (2015)

Cytoskeleton Reorganization in EndMT—The Role in Cancer and Fibrotic Diseases
por: Ciszewski, Wojciech Michał, et al.
Publicado: (2021)

Modulation of EndMT by Hydrogen Sulfide in the Prevention of Cardiovascular Fibrosis
por: Testai, Lara, et al.
Publicado: (2021)

EMT and EndMT: Emerging Roles in Age-Related Macular Degeneration
por: Shu, Daisy Y., et al.
Publicado: (2020)

MicroRNAs in Kidney Fibrosis and Diabetic Nephropathy: Roles on EMT and EndMT
por: Srivastava, Swayam Prakash, et al.
Publicado: (2013)

EndMT: New findings on the origin of myofibroblasts in endometrial fibrosis of intrauterine adhesions
por: Xu, Chengcheng, et al.
Publicado: (2022)

Single cell meta-analysis of EndMT and EMT state in COVID-19
por: Zhang, Lanlan, et al.
Publicado: (2022)

Single Cell Meta-Analysis of Endothelial to Mesenchymal Transition (EndMT) in Glucose Metabolism of the Digestive Diseases
por: Zhou, Qiao, et al.
Publicado: (2022)

Identification of radiation‐induced EndMT inhibitors through cell‐based phenomic screening
por: Song, Yeonhwa, et al.
Publicado: (2018)

Cripto shapes macrophage plasticity and restricts EndMT in injured and diseased skeletal muscle
por: Iavarone, Francescopaolo, et al.
Publicado: (2020)

Correction to: EndMT: New fndings on the origin of myofbroblasts in endometrial fbrosis of intrauterine adhesions
por: Xu, Chengcheng, et al.
Publicado: (2022)

Protective Effects of Eicosapentaenoic Acid on the Glomerular Endothelium via Inhibition of EndMT in Diabetes
por: Yasuzawa, Toshinori, et al.
Publicado: (2021)

Endothelial to mesenchymal transition (EndMT): an active process in Chronic Obstructive Pulmonary Disease (COPD)?
por: Sohal, Sukhwinder Singh
Publicado: (2016)

Local and Circulating Endothelial Cells Undergo Endothelial to Mesenchymal Transition (EndMT) in Response to Musculoskeletal Injury
por: Agarwal, Shailesh, et al.
Publicado: (2016)

EndMT Regulation by Small RNAs in Diabetes-Associated Fibrotic Conditions: Potential Link With Oxidative Stress
por: Giordo, Roberta, et al.
Publicado: (2021)

SIRT1 mediates the inhibitory effect of Dapagliflozin on EndMT by inhibiting the acetylation of endothelium Notch1
por: Wang, Weijie, et al.
Publicado: (2023)

KMT5A downregulation participated in High Glucose-mediated EndMT via Upregulation of ENO1 Expression in Diabetic Nephropathy
por: Lu, Lihong, et al.
Publicado: (2021)

Mechanisms of the Osteogenic Switch of Smooth Muscle Cells in Vascular Calcification: WNT Signaling, BMPs, Mechanotransduction, and EndMT
por: Tyson, John, et al.
Publicado: (2020)

Endothelial eNAMPT drives EndMT and preclinical PH: rescue by an eNAMPT-neutralizing mAb
por: Ahmed, Mohamed, et al.
Publicado: (2021)

Calcium-Sensing Receptor Participates in High Glucose-Induced EndMT in Primary Human Aortic Endothelial Cells
por: Yuan, Cheng, et al.
Publicado: (2021)

The SETD8/ELK1/bach1 complex regulates hyperglycaemia-mediated EndMT in diabetic nephropathy
por: Li, Xue, et al.
Publicado: (2022)

PECAM-1 drives β-catenin-mediated EndMT via internalization in colon cancer with diabetes mellitus
por: Wu, Qing, et al.
Publicado: (2023)

miR-190a-5p Partially Represses the Abnormal Electrical Activity of SCN3B in Cardiac Arrhythmias by Downregulation of IL-2
por: Li, Qianqian, et al.
Publicado: (2022)

Dapagliflozin alleviates cardiac fibrosis through suppressing EndMT and fibroblast activation via AMPKα/TGF‐β/Smad signalling in type 2 diabetic rats
por: Tian, Jingjing, et al.
Publicado: (2021)

27-Hydroxycholesterol-induced EndMT acts via STAT3 signaling to promote breast cancer cell migration by altering the tumor microenvironment
por: Jiao, Kailin, et al.
Publicado: (2020)

TLR2 regulates angiotensin II-induced vascular remodeling and EndMT through NF-κB signaling
por: Lin, Ke, et al.
Publicado: (2020)

A novel Nanocellulose-Gelatin-AS-IV external stent resists EndMT by activating autophagy to prevent restenosis of grafts
por: Chu, Tianshu, et al.
Publicado: (2022)

Single-cell sequencing reveals that endothelial cells, EndMT cells and mural cells contribute to the pathogenesis of cavernous malformations
por: Ren, Jian, et al.
Publicado: (2023)

GDF15 affects venous thrombosis by promoting EndMT through smad2/p-smad2 pathway
por: Li, Yeping, et al.
Publicado: (2023)

Aspirin-Triggered Resolvin D1 Inhibits TGF-β1-Induced EndMT through Increasing the Expression of Smad7 and Is Closely Related to Oxidative Stress
por: Shu, Yusheng, et al.
Publicado: (2016)

Single-cell RNA-seq reveals a critical role of novel pro-inflammatory EndMT in mediating adverse remodeling in coronary artery–on–a–chip
por: Zhao, Peng, et al.
Publicado: (2021)

The Carthamus tinctorius L. and Lepidium apetalum Willd. Drug Pair Inhibits EndMT through the TGFβ1/Snail Signaling Pathway in the Treatment of Myocardial Fibrosis
por: Zhou, Zhou, et al.
Publicado: (2023)

LncRNA MALAT1 modulates ox-LDL induced EndMT through the Wnt/β-catenin signaling pathway
por: Li, Hongrong, et al.
Publicado: (2019)

Dexmedetomidine Protects Against Kidney Fibrosis in Diabetic Mice by Targeting miR-101-3p-Mediated EndMT
por: Song, Li, et al.
Publicado: (2022)

KRAS mutation-induced EndMT of brain arteriovenous malformation is mediated through the TGF-β/BMP-SMAD4 pathway
por: Xu, Hongyuan, et al.
Publicado: (2022)

MED12 Regulates Smooth Muscle Cell Functions and Participates in the Development of Aortic Dissection
por: Zhou, Yingchao, et al.
Publicado: (2022)

Saikosaponin A Protects From Pressure Overload-Induced Cardiac Fibrosis via Inhibiting Fibroblast Activation or Endothelial Cell EndMT
por: Liu, Yuan, et al.
Publicado: (2018)

A reciprocal feedback of miR-548ac/YB-1/Snail induces EndMT of HUVECs during acidity microenvironment
por: Chen, Jingyuan, et al.
Publicado: (2021)

EP4 Agonist L-902,688 Suppresses EndMT and Attenuates Right Ventricular Cardiac Fibrosis in Experimental Pulmonary Arterial Hypertension
por: Lai, Ying-Ju, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_s0phau3iu0vc71p5vpmbth2r0c