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Integrative transcriptomic and proteomic analysis reveals CD9/ITGA4/PI3K‐Akt axis mediates trabecular meshwork cell apoptosis in human glaucoma

Glaucoma has been the leading cause of irreversible blindness worldwide. High intraocular pressure (IOP) is a high‐risk factor of glaucoma, repression of which has been the important treatment of glaucoma in clinic. Trabecular meshwork is crucial for maintaining IOP in aqueous humour out‐flow system...

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Detalles Bibliográficos
Autores principales: Yan, Junwei, Yang, Xuejiao, Jiao, Xuefei, Yang, Xian, Guo, Mingjin, Chen, Yunqing, Zhan, Lu, Chen, Wenshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933396/
https://www.ncbi.nlm.nih.gov/pubmed/31680442
http://dx.doi.org/10.1111/jcmm.14792

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