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DNA Methylation Changes More Slowly Than Physiological States in Response to Weight Loss in Genetically Diverse Mouse Strains

Responses to a high fat, high sucrose (HFHS) diet vary greatly among inbred strains of mice. We sought to examine the epigenetic (DNA methylation) changes underlying these differences as well as variation in weight loss when switched to a low-fat chow diet. We surveyed DNA methylation from livers of...

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Detalles Bibliográficos
Autores principales: Edillor, Chantle R., Parks, Brian W., Mehrabian, Margarete, Lusis, Aldons J., Pellegrini, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933503/
https://www.ncbi.nlm.nih.gov/pubmed/31920990
http://dx.doi.org/10.3389/fendo.2019.00882