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Microtubules Stabilization by Mutant Spastin Affects ER Morphology and Ca(2+) Handling

The endoplasmic reticulum (ER) extends as a network of interconnected tubules and sheet-like structures in eukaryotic cells. ER tubules dynamically change their morphology and position within the cells in response to physiological stimuli and these network rearrangements depend on the microtubule (M...

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Detalles Bibliográficos
Autores principales: Vajente, Nicola, Norante, Rosa, Redolfi, Nelly, Daga, Andrea, Pizzo, Paola, Pendin, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933510/
https://www.ncbi.nlm.nih.gov/pubmed/31920731
http://dx.doi.org/10.3389/fphys.2019.01544