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Induction of tryptophan 2,3-dioxygenase expression in human monocytic leukemia/lymphoma cell lines THP-1 and U937

Tumor-associated macrophages are immune cells with diverse functions in tumor development. Among other functions, they downregulate immune-mediated tumor rejection by depriving lymphocytes of nutrients. The essential amino acid tryptophan is metabolized by the enzymes indoleamine 2,3-dioxygenase 1 a...

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Detalles Bibliográficos
Autores principales:	Hoffmann, Delia, Pilotte, Luc, Stroobant, Vincent, Van den Eynde, Benoit J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933542/ https://www.ncbi.nlm.nih.gov/pubmed/31903023 http://dx.doi.org/10.1177/1178646919891736

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