Cargando…

New Findings in the Signaling Pathways of cis and trans Platinum Iodido Complexes’ Interaction with DNA of Cancer Cells

[Image: see text] We have selected a series of aliphatic amine platinum compounds bearing chloride and/or iodide as the leaving groups. The complexes’ cytotoxicity and interaction with DNA indicated differences in the reactivity. Now, we are reporting on the analysis of their molecular mechanism of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Quiroga, Adoración G., Cama, Marta, Pajuelo-Lozano, Natalia, Álvarez-Valdés, Amparo, Sanchez Perez, Isabel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2019
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933576/ https://www.ncbi.nlm.nih.gov/pubmed/31891063 http://dx.doi.org/10.1021/acsomega.9b02831

Ejemplares similares

Using phosphine ligands with a biological role to modulate reactivity in novel platinum complexes
por: Echeverri, Marcelo, et al.
Publicado: (2018)

XPA, XPC, and XPD Modulate Sensitivity in Gastric Cisplatin Resistance Cancer Cells
por: Pajuelo-Lozano, Natalia, et al.
Publicado: (2018)

Crystal structure and Hirshfeld analysis of trans-diiodidobis[(methylsulfanyl)benzene-κS]platinum(II)
por: Schmidt, Annika, et al.
Publicado: (2023)

(5,5′-Dimethyl-2,2′-bipyridine)iodidotrimethylplatinum(IV)
por: Lundvall, Fredrik, et al.
Publicado: (2011)

Platinum(II) Iodido Complexes of 7-Azaindoles with Significant Antiproliferative Effects: An Old Story Revisited with Unexpected Outcomes
por: Štarha, Pavel, et al.
Publicado: (2016)

Mechanistic added value of a trans-Sulfonamide-Platinum-Complex in human melanoma cell lines and synergism with cis-Platin
por: Agudo-López, Alba, et al.
Publicado: (2017)

Cellular Uptake, DNA Binding and Apoptosis Induction of Cytotoxic Trans-[PtCl(2)(N,N-dimethylamine)(Isopropylamine)] in A2780cisR Ovarian Tumor Cells
por: Pérez, José M., et al.
Publicado: (2001)

catena-Poly[[trans-bis(cyclohexane-1,2-diamine-κ(2) N,N)cadmium]-μ-iodido-(diiodidocadmium)-μ-iodido]
por: Cui, Sheng-Feng, et al.
Publicado: (2012)

Redetermination of the crystal structure of catena-poly[[[bis(ethylenediamine)platinum(II)]-μ-iodido-[bis(ethylenediamine)platinum(IV)]-μ-iodido] tetrakis(octane-1-sulfonate) dihydrate]
por: Matsushita, Nobuyuki
Publicado: (2015)

Tetra(chlorido/iodido)(1,10-phenanthroline)platinum(IV) hemi[di(chlorine/iodine)]
por: Kim, Nam-Ho, et al.
Publicado: (2009)

Sister chromatid exchanges induced by two radiosensitizing platinum compounds (cis-dichloro-bis isopropylamine trans dihydroxy platinum IV (CHIP) and cis platinum metronidazole2Cl2(FLAP] in CHO cells in vitro.
por: Bocian, E., et al.
Publicado: (1983)

trans-Iodido(pyrazinyl-κC (2))bis(triphenylphosphane-κP)palladium(II)
por: Tu, Yao-Jen, et al.
Publicado: (2012)

Synthesis and structure of two novel trans-platinum complexes
por: Vinci, Doriana, et al.
Publicado: (2023)

A highly constrained cis-dihydride platinum complex trapped by cooperative gold/platinum dihydrogen activation
por: Hidalgo, Nereida, et al.
Publicado: (2022)

Palladium and Platinum 2,4-cis-amino Azetidine and Related Complexes
por: Yoshizawa, Akina, et al.
Publicado: (2018)

Bis(tetraphenylphosphonium) di-μ-iodido-bis[diiodidotellurate(II)]
por: Närhi, Sari M., et al.
Publicado: (2008)

trans-Di-μ-iodido-bis[(3H-1,2-benzodithiole-3-thione)iodidomercury(II)]
por: Laifa, El Adoui, et al.
Publicado: (2009)

Combination studies with misonidazole and a cis-platinum complex: cytotoxicity and radiosensitization in vitro.
por: Stratford, I. J., et al.
Publicado: (1980)

cis-Dichloridobis(triisopropoxyphosphine)platinum(II)
por: Slawin, Alexandra M. Z., et al.
Publicado: (2009)

Polymorphic Cis- and Trans-Regulation of Human Gene Expression
por: Cheung, Vivian G., et al.
Publicado: (2010)

Trans-, cis-, and dihydro-resveratrol: a comparative study
por: Anisimova, Natalia YU, et al.
Publicado: (2011)

Cis- and trans-regulation in X inactivation
por: van Bemmel, Joke G., et al.
Publicado: (2015)

Relative Stability of cis- and trans-Hydrindanones
por: Tori, Motoo
Publicado: (2015)

The mode of action of cis dichloro-bis (isopropylamine) trans dihydroxy platinum IV (CHIP) studied by the analysis of chromosome aberration production.
por: Bocian, E., et al.
Publicado: (1983)

Small intestinal mucosal toxicity of cis-platinum--comparison of toxicity with platinum analogues and dexamethasone.
por: Allan, S. G., et al.
Publicado: (1986)

A double salt of iodobismuthate: cis-aquaiodidobis(1,10-phenanthroline)cobalt(II) tris(1,10-phenanthroline)cobalt(II) trans-hexa-μ(2)-iodido-hexaiodidotribismuthate(III)
por: Chen, Jiongke, et al.
Publicado: (2011)

Cyclodextrin Inclusion Complexes of Auranofin and Its Iodido Analog: A Chemical and Biological Study
por: Cirri, Damiano, et al.
Publicado: (2021)

cis-Dimethylbis(triphenylarsine)platinum(II)
por: Abo-Amer, Anwar
Publicado: (2010)

Bis(tetrapropylammonium) di-μ(3)-iodido-di-μ(2)-iodido-diiodidodipyridinetetracopper(I)
por: Jalilian, Ehsan
Publicado: (2010)

Di-μ-iodido-bis{[(4-fluorobenzoylmethylene)triphenyl-λ(5)-phosphorane]iodidomercury(II)}
por: Akkurt, Mehmet, et al.
Publicado: (2008)

Targeting MAD2 modulates stemness and tumorigenesis in human Gastric Cancer cell lines
por: Pajuelo-Lozano, Natalia, et al.
Publicado: (2020)

Cis and trans effects differentially contribute to the evolution of promoters and enhancers
por: Mattioli, Kaia, et al.
Publicado: (2020)

Crystal structure of bis(diisopropylammonium) cis-diiodidobis(oxolato-κ(2) O (1),O (2))stannate(IV)
por: Sarr, Bougar, et al.
Publicado: (2018)

cis–trans Isomerization of silybins A and B
por: Novotná, Michaela, et al.
Publicado: (2014)

cis-platinum and ovarian carcinoma. In vitro chemosensitivity of cultured tumour cells from patients receiving high dose cis-platinum as first line treatment.
por: Wilson, A. P., et al.
Publicado: (1987)

Assembly and disassembly of the Golgi complex: two processes arranged in a cis-trans direction
Publicado: (1992)

catena-Poly[[bis(μ(2)-1,4,7,10,13,16-hexaoxacyclooctadecane)dipotassium]-μ(2)-iodido-(iodidocadmium)-di-μ(2)-iodido-(iodidocadmium)-μ(2)-iodido]
por: Rajarajan, K., et al.
Publicado: (2013)

UVA-Photosensitivity of cis-Diamminedichloro-Platinum(II)-Modified DNA
por: Payet, Dominique, et al.
Publicado: (1995)

cis-Bis(2-sulfidopyridine N-oxide)platinum(II)
por: Ravindran Durai Nayagam, B., et al.
Publicado: (2008)

cis-Tetrachloridobis(1H-imidazole-κN (3))platinum(IV)
por: Bokach, Nadezhda A., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_kql4cjl0ad1vf8aqlegpu9fn5c