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Molecular Mechanism of the Antiproliferative Activity of Short Immunostimulating dsRNA
Small double-stranded RNAs with certain sequence motifs are able to interact with pattern-recognition receptors and activate the innate immune system. Recently, we identified a set of short double-stranded 19-bp RNA molecules with 3-nucleotide 3′-overhangs that exhibited pronounced antiproliferative...
Autores principales: | Zharkov, Mikhail I., Zenkova, Marina A., Vlassov, Valentin V., Chernolovskaya, Elena L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933605/ https://www.ncbi.nlm.nih.gov/pubmed/31921696 http://dx.doi.org/10.3389/fonc.2019.01454 |
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