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IL-17A-Mediated Excessive Autophagy Aggravated Neuronal Ischemic Injuries via Src-PP2B-mTOR Pathway

We previously reported that astrocyte-derived proinflammatory cytokine interleukin (IL)-17A could aggravate neuronal ischemic injuries and strength autophagy both in oxygen-glucose deprivation (OGD)/reoxygenation (R)-treated neurons and peri-infarct region of mice with middle cerebral artery occlusi...

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Detalles Bibliográficos
Autores principales: Liu, Ting, Han, Song, Dai, Qingqing, Zheng, Jiayin, Liu, Cui, Li, Shujuan, Li, Junfa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933613/
https://www.ncbi.nlm.nih.gov/pubmed/31921197
http://dx.doi.org/10.3389/fimmu.2019.02952