Cargando…

Palmitoylethanolamide counteracts substance P-induced mast cell activation in vitro by stimulating diacylglycerol lipase activity

BACKGROUND: Palmitoylethanolamide (PEA) is a pleiotropic endogenous lipid mediator currently used as a “dietary food for special medical purposes” against neuropathic pain and neuro-inflammatory conditions. Several mechanisms underlie PEA actions, among which the “entourage” effect, consisting of PE...

Descripción completa

Detalles Bibliográficos
Autores principales:	Petrosino, Stefania, Schiano Moriello, Aniello, Verde, Roberta, Allarà, Marco, Imperatore, Roberta, Ligresti, Alessia, Mahmoud, Ali Mokhtar, Peritore, Alessio Filippo, Iannotti, Fabio Arturo, Di Marzo, Vincenzo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933707/ https://www.ncbi.nlm.nih.gov/pubmed/31878942 http://dx.doi.org/10.1186/s12974-019-1671-5

Ejemplares similares

A Glucuronic Acid-Palmitoylethanolamide Conjugate (GLUPEA) Is an Innovative Drug Delivery System and a Potential Bioregulator
por: Manzo, Emiliano, et al.
Publicado: (2021)

Oral Ultramicronized Palmitoylethanolamide: Plasma and Tissue Levels and Spinal Anti-hyperalgesic Effect
por: Petrosino, Stefania, et al.
Publicado: (2018)

First Evidence of the Protective Effects of 2-Pentadecyl-2-Oxazoline (PEA-OXA) in In Vitro Models of Acute Lung Injury
por: Schiano Moriello, Aniello, et al.
Publicado: (2022)

Palmitoylethanolamide: A Nutritional Approach to Keep Neuroinflammation within Physiological Boundaries—A Systematic Review
por: Petrosino, Stefania, et al.
Publicado: (2020)

Palmitoylethanolamide counteracts reactive astrogliosis induced by β-amyloid peptide
por: Scuderi, Caterina, et al.
Publicado: (2011)

Mutual Links between the Endocannabinoidome and the Gut Microbiome, with Special Reference to Companion Animals: A Nutritional Viewpoint †
por: Schiano Moriello, Aniello, et al.
Publicado: (2022)

Palmitoylethanolamide induces microglia changes associated with increased migration and phagocytic activity: involvement of the CB2 receptor
por: Guida, F., et al.
Publicado: (2017)

Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain
por: Bisogno, Tiziana, et al.
Publicado: (2003)

Increased levels of palmitoylethanolamide and other bioactive lipid mediators and enhanced local mast cell proliferation in canine atopic dermatitis
por: Abramo, Francesca, et al.
Publicado: (2014)

Possible Anandamide and Palmitoylethanolamide involvement in human stroke
por: Naccarato, Marcello, et al.
Publicado: (2010)

Engineering the Thermostability of the Mono- and Diacylglycerol Lipase SMG1 for the Synthesis of Diacylglycerols
por: Li, Lilang, et al.
Publicado: (2022)

Palmitoylethanolamide reduces granuloma-induced hyperalgesia by modulation of mast cell activation in rats
por: De Filippis, Daniele, et al.
Publicado: (2011)

The endocannabinoidome mediator N-oleoylglycine is a novel protective agent against 1-methyl-4-phenyl-pyridinium-induced neurotoxicity
por: Lauritano, Anna, et al.
Publicado: (2022)

A novel live cell assay to measure diacylglycerol lipase α activity
por: Singh, Praveen K., et al.
Publicado: (2016)

Impaired Duodenal Palmitoylethanolamide Release Underlies Acid-Induced Mast Cell Activation in Functional Dyspepsia
por: Sarnelli, Giovanni, et al.
Publicado: (2020)

Management of Acute Lung Injury: Palmitoylethanolamide as a New Approach
por: Peritore, Alessio Filippo, et al.
Publicado: (2021)

Contribution of diacylglycerol lipase β to pain after surgery
por: Luk, Jennifer, et al.
Publicado: (2018)

Inhibition of Diacylglycerol Lipase Impairs Fear Extinction in Mice
por: Cavener, Victoria S., et al.
Publicado: (2018)

Effects of Starvation on the Levels of Triglycerides, Diacylglycerol, and Activity of Lipase in Male and Female Drosophila Melanogaster
por: Chauhan, Ved, et al.
Publicado: (2021)

Localization of diacylglycerol lipase alpha and monoacylglycerol lipase during postnatal development of the rat retina
por: Cécyre, Bruno, et al.
Publicado: (2014)

Endocannabinoids Generated by Ca(2+) or by Metabotropic Glutamate Receptors Appear to Arise from Different Pools of Diacylglycerol Lipase
por: Zhang, Longhua, et al.
Publicado: (2011)

Ultramicronized Palmitoylethanolamide in the Management of Sepsis-Induced Coagulopathy and Disseminated Intravascular Coagulation
por: D’Amico, Ramona, et al.
Publicado: (2021)

Palmitoylethanolamide Supplementation during Sensitization Prevents Airway Allergic Symptoms in the Mouse
por: Roviezzo, Fiorentina, et al.
Publicado: (2017)

Diacylglycerol lipase alpha promotes hepatocellular carcinoma progression and induces lenvatinib resistance by enhancing YAP activity
por: Yan, Yu-Chuan, et al.
Publicado: (2023)

Palmitoylethanolamide and Related ALIAmides: Prohomeostatic Lipid Compounds for Animal Health and Wellbeing
por: Gugliandolo, Enrico, et al.
Publicado: (2020)

The Protective Effects of Pre- and Post-Administration of Micronized Palmitoylethanolamide Formulation on Postoperative Pain in Rats
por: Siracusa, Rosalba, et al.
Publicado: (2020)

Palmitoylethanolamide Counteracts Enteric Inflammation and Bowel Motor Dysfunctions in a Mouse Model of Alzheimer’s Disease
por: D’Antongiovanni, Vanessa, et al.
Publicado: (2021)

Intestinal Disorder in Zebrafish Larvae (Danio rerio): The Protective Action of N-Palmitoylethanolamide-oxazoline
por: Di Paola, Davide, et al.
Publicado: (2022)

Identification and Characterization of Cannabidiol as an OX1R Antagonist by Computational and In Vitro Functional Validation
por: Vitale, Rosa Maria, et al.
Publicado: (2021)

CaMKII Modulates Diacylglycerol Lipase-α Activity in the Rat Nucleus Accumbens after Incubation of Cocaine Craving
por: Murray, Conor H., et al.
Publicado: (2021)

Palmitoylethanolamide and White Matter Lesions: Evidence for Therapeutic Implications
por: Valenza, Marta, et al.
Publicado: (2022)

Diacylglycerol lipase α manipulation reveals developmental roles for intercellular endocannabinoid signaling
por: Keimpema, Erik, et al.
Publicado: (2013)

ABHD11, a new diacylglycerol lipase involved in weight gain regulation
por: Escoubet, Johanna, et al.
Publicado: (2020)

Regulation of adult neurogenesis by the endocannabinoid-producing enzyme diacylglycerol lipase alpha (DAGLa)
por: Schuele, Lena-Louise, et al.
Publicado: (2022)

Therapeutic Efficacy of Palmitoylethanolamide and Its New Formulations in Synergy with Different Antioxidant Molecules Present in Diets
por: Peritore, Alessio Filippo, et al.
Publicado: (2019)

Modulation of mRNA Expression of Monoacylglycerol Lipase, Diacylglycerol Lipase and Cannabinoid Receptor-1 in Mice Experimentally Infected with T. gondii
por: Rostami-Mansoor, Sahar, et al.
Publicado: (2021)

Exploiting Nanotechnologies and TRPV1 Channels to Investigate the Putative Anandamide Membrane Transporter
por: Ligresti, Alessia, et al.
Publicado: (2010)

Ultramicronized Palmitoylethanolamide and Paracetamol, a New Association to Relieve Hyperalgesia and Pain in a Sciatic Nerve Injury Model in Rat
por: Peritore, Alessio Filippo, et al.
Publicado: (2020)

CaMKII is a novel regulator of diacylglycerol lipase-α and striatal endocannabinoid signaling
por: Shonesy, Brian C., et al.
Publicado: (2013)

Palmitoylethanolamide counteracts high-fat diet-induced gut dysfunction by reprogramming microbiota composition and affecting tryptophan metabolism
por: Pirozzi, Claudio, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_neqjok627nqpj1iusos477mfks