New (99m)Tc-Labeled Digitoxigenin Derivative for Cancer Cell Identification

[Image: see text] In recent years, cardiac glycosides (CGs) have been investigated as potential antiviral and anticancer drugs. Digitoxigenin (DIG) and other CGs have been shown to bind and inhibit Na(+)/K(+)-adenosinetriphosphatase (ATPase). Tumor cells show a higher expression rate of the Na(+)/K(...

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Detalles Bibliográficos
Autores principales: Munkert, Jennifer, Gomes, Eliza R., Marostica, Lucas L., Cota, Betânia B., Lopes, Cristina L. M., Andrade, Saulo F., Filho, José D. de Souza, Alves, Ricardo J., Oliveira, Monica C., Braga, Fernão C., Simões, Cláudia M. O., Pádua, Rodrigo M., de Barros, André L. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933791/
https://www.ncbi.nlm.nih.gov/pubmed/31891085
http://dx.doi.org/10.1021/acsomega.9b03167

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