The ERβ5 splice variant increases oestrogen responsiveness of ERα(pos) Ishikawa cells

Endometrial cancer is a common gynaeological malignancy: life time exposure to oestrogen is a key risk factor. Oestrogen action is mediated by receptors encoded by ESR1 (ERα) and ESR2 (ERβ): ERα plays a key role in regulating endometrial cell proliferation. A truncated splice variant isoform (ERβ5)...

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Detalles Bibliográficos
Autores principales: Collins, Frances, Itani, Nozomi, Esnal-Zufiaurre, Arantza, Gibson, Douglas A, Fitzgerald, Carol, Saunders, Philippa T K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933808/
https://www.ncbi.nlm.nih.gov/pubmed/31778358
http://dx.doi.org/10.1530/ERC-19-0291

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933808/
https://www.ncbi.nlm.nih.gov/pubmed/31778358
http://dx.doi.org/10.1530/ERC-19-0291

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