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AR mRNA stability is increased with AR-antagonist resistance via 3′UTR variants

Advanced prostate cancer is often treated with AR antagonists which target the androgen receptor (AR) on which the growth of the tumour depends. Prostate cancer often develops AR-antagonist resistance via a plethora of mechanisms, many of which are as yet unknown, but it is thought that AR upregulat...

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Detalles Bibliográficos
Autores principales:	Dart, D A, Ashelford, K, Jiang, W G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bioscientifica Ltd 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933836/ https://www.ncbi.nlm.nih.gov/pubmed/31778359 http://dx.doi.org/10.1530/EC-19-0340

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