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The Dundee Resource for Sequence Analysis and Structure Prediction

The Dundee Resource for Sequence Analysis and Structure Prediction (DRSASP; http://www.compbio.dundee.ac.uk/drsasp.html) is a collection of web services provided by the Barton Group at the University of Dundee. DRSASP's flagship services are the JPred4 webserver for secondary structure and solv...

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Autores principales: MacGowan, Stuart A., Madeira, Fábio, Britto‐Borges, Thiago, Warowny, Mateusz, Drozdetskiy, Alexey, Procter, James B., Barton, Geoffrey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933851/
https://www.ncbi.nlm.nih.gov/pubmed/31710725
http://dx.doi.org/10.1002/pro.3783
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author MacGowan, Stuart A.
Madeira, Fábio
Britto‐Borges, Thiago
Warowny, Mateusz
Drozdetskiy, Alexey
Procter, James B.
Barton, Geoffrey J.
author_facet MacGowan, Stuart A.
Madeira, Fábio
Britto‐Borges, Thiago
Warowny, Mateusz
Drozdetskiy, Alexey
Procter, James B.
Barton, Geoffrey J.
author_sort MacGowan, Stuart A.
collection PubMed
description The Dundee Resource for Sequence Analysis and Structure Prediction (DRSASP; http://www.compbio.dundee.ac.uk/drsasp.html) is a collection of web services provided by the Barton Group at the University of Dundee. DRSASP's flagship services are the JPred4 webserver for secondary structure and solvent accessibility prediction and the JABAWS 2.2 webserver for multiple sequence alignment, disorder prediction, amino acid conservation calculations, and specificity‐determining site prediction. DRSASP resources are available through conventional web interfaces and APIs but are also integrated into the Jalview sequence analysis workbench, which enables the composition of multitool interactive workflows. Other existing Barton Group tools are being brought under the banner of DRSASP, including NoD (Nucleolar localization sequence detector) and 14‐3‐3‐Pred. New resources are being developed that enable the analysis of population genetic data in evolutionary and 3D structural contexts. Existing resources are actively developed to exploit new technologies and maintain parity with evolving web standards. DRSASP provides substantial computational resources for public use, and since 2016 DRSASP services have completed over 1.5 million jobs.
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spelling pubmed-69338512019-12-30 The Dundee Resource for Sequence Analysis and Structure Prediction MacGowan, Stuart A. Madeira, Fábio Britto‐Borges, Thiago Warowny, Mateusz Drozdetskiy, Alexey Procter, James B. Barton, Geoffrey J. Protein Sci Tools for Protein Science The Dundee Resource for Sequence Analysis and Structure Prediction (DRSASP; http://www.compbio.dundee.ac.uk/drsasp.html) is a collection of web services provided by the Barton Group at the University of Dundee. DRSASP's flagship services are the JPred4 webserver for secondary structure and solvent accessibility prediction and the JABAWS 2.2 webserver for multiple sequence alignment, disorder prediction, amino acid conservation calculations, and specificity‐determining site prediction. DRSASP resources are available through conventional web interfaces and APIs but are also integrated into the Jalview sequence analysis workbench, which enables the composition of multitool interactive workflows. Other existing Barton Group tools are being brought under the banner of DRSASP, including NoD (Nucleolar localization sequence detector) and 14‐3‐3‐Pred. New resources are being developed that enable the analysis of population genetic data in evolutionary and 3D structural contexts. Existing resources are actively developed to exploit new technologies and maintain parity with evolving web standards. DRSASP provides substantial computational resources for public use, and since 2016 DRSASP services have completed over 1.5 million jobs. John Wiley & Sons, Inc. 2019-11-28 2020-01 /pmc/articles/PMC6933851/ /pubmed/31710725 http://dx.doi.org/10.1002/pro.3783 Text en © 2019 The Authors. Protein Science published by Wiley Periodicals, Inc. on behalf of The Protein Society. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Tools for Protein Science
MacGowan, Stuart A.
Madeira, Fábio
Britto‐Borges, Thiago
Warowny, Mateusz
Drozdetskiy, Alexey
Procter, James B.
Barton, Geoffrey J.
The Dundee Resource for Sequence Analysis and Structure Prediction
title The Dundee Resource for Sequence Analysis and Structure Prediction
title_full The Dundee Resource for Sequence Analysis and Structure Prediction
title_fullStr The Dundee Resource for Sequence Analysis and Structure Prediction
title_full_unstemmed The Dundee Resource for Sequence Analysis and Structure Prediction
title_short The Dundee Resource for Sequence Analysis and Structure Prediction
title_sort dundee resource for sequence analysis and structure prediction
topic Tools for Protein Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933851/
https://www.ncbi.nlm.nih.gov/pubmed/31710725
http://dx.doi.org/10.1002/pro.3783
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