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Genetic perturbations of disease risk genes in mice capture transcriptomic signatures of late-onset Alzheimer’s disease

BACKGROUND: New genetic and genomic resources have identified multiple genetic risk factors for late-onset Alzheimer’s disease (LOAD) and characterized this common dementia at the molecular level. Experimental studies in model organisms can validate these associations and elucidate the links between...

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Detalles Bibliográficos
Autores principales:	Pandey, Ravi S., Graham, Leah, Uyar, Asli, Preuss, Christoph, Howell, Gareth R., Carter, Gregory W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933917/ https://www.ncbi.nlm.nih.gov/pubmed/31878951 http://dx.doi.org/10.1186/s13024-019-0351-3

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