Cargando…

Mitochondrial ROS promote macrophage pyroptosis by inducing GSDMD oxidation

Disrupted mitochondrial membrane potential (MMP) and reactive oxygen species (ROS) generation are often associated with macrophage pyroptosis. It remains unclear how these forms of mitochondrial dysfunction relate to inflammasome activation and gasdermin-D (Gsdmd) cleavage, two central steps of the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Yufang, Shi, Peiliang, Chen, Qin, Huang, Zan, Zou, Dayuan, Zhang, Jingzi, Gao, Xiang, Lin, Zhaoyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934151/ https://www.ncbi.nlm.nih.gov/pubmed/30860577 http://dx.doi.org/10.1093/jmcb/mjz020

Ejemplares similares

Fatty acid oxidation promotes reprogramming by enhancing oxidative phosphorylation and inhibiting protein kinase C
por: Lin, Zhaoyu, et al.
Publicado: (2018)

Correction to: Fatty acid oxidation promotes reprogramming by enhancing oxidative phosphorylation and inhibiting protein kinase C
por: Lin, Zhaoyu, et al.
Publicado: (2018)

GSDMD-Mediated Cardiomyocyte Pyroptosis Promotes Myocardial I/R Injury
por: Shi, Huairui, et al.
Publicado: (2021)

Simvastatin induces pyroptosis via ROS/caspase-1/GSDMD pathway in colon cancer
por: Xie, Wei, et al.
Publicado: (2023)

Blocking Caspase-1/Gsdmd and Caspase-3/-8/Gsdme pyroptotic pathways rescues silicosis in mice
por: Kang, Lulu, et al.
Publicado: (2022)

GSDMD-mediated pyroptosis restrains intracellular Chlamydia trachomatis growth in macrophages
por: Jiang, Ping, et al.
Publicado: (2023)

TSPO Deficiency Exacerbates GSDMD-Mediated Macrophage Pyroptosis in Inflammatory Bowel Disease
por: Zhang, Xue, et al.
Publicado: (2022)

Tetracaine hydrochloride induces macrophage pyroptosis through caspase‑1/11‑GSDMD signaling pathways
por: Zhang, Ran, et al.
Publicado: (2023)

GSDMD contributes to myocardial reperfusion injury by regulating pyroptosis
por: Ye, Xiaomiao, et al.
Publicado: (2022)

GSDMD-mediated pyroptosis: a critical mechanism of diabetic nephropathy
por: Zuo, Yi, et al.
Publicado: (2021)

Jatrorrhizine Suppresses Murine-Norovirus-Triggered N-GSDMD-Dependent Pyroptosis in RAW264.7 Macrophages
por: Fu, Ming, et al.
Publicado: (2023)

Hemoglobin Derived from Subarachnoid Hemorrhage-Induced Pyroptosis of Neural Stem Cells via ROS/NLRP3/GSDMD Pathway
por: Yue, Tingting, et al.
Publicado: (2023)

Ceramide induces pyroptosis through TXNIP/NLRP3/GSDMD pathway in HUVECs
por: Liu, Fangfang, et al.
Publicado: (2022)

LPS Enhances the Chemosensitivity of Oxaliplatin in HT29 Cells via GSDMD-Mediated Pyroptosis
por: Wu, Li-Sha, et al.
Publicado: (2020)

Myoglobin promotes macrophage polarization to M1 type and pyroptosis via the RIG-I/Caspase1/GSDMD signaling pathway in CS-AKI
por: Li, Ning, et al.
Publicado: (2022)

Oridonin Protects against Myocardial Ischemia–Reperfusion Injury by Inhibiting GSDMD-Mediated Pyroptosis
por: Lin, Jiahui, et al.
Publicado: (2022)

Pyroptosis executive protein GSDMD as a biomarker for diagnosis and identification of Alzheimer’s disease
por: Shen, Heping, et al.
Publicado: (2021)

IRF2 contributes to myocardial infarction via regulation of GSDMD induced pyroptosis
por: Li, Yongxing, et al.
Publicado: (2022)

Disulfiram alleviates pristane-induced lupus via inhibiting GSDMD-mediated pyroptosis
por: Zhuang, Lili, et al.
Publicado: (2022)

Bcl-2 regulates pyroptosis and necroptosis by targeting BH3-like domains in GSDMD and MLKL
por: Shi, Chong-Shan, et al.
Publicado: (2019)

Direct Inhibition of GSDMD by PEITC Reduces Hepatocyte Pyroptosis and Alleviates Acute Liver Injury in Mice
por: Wang, Jie, et al.
Publicado: (2022)

E3 ubiquitin ligase SYVN1 is a key positive regulator for GSDMD-mediated pyroptosis
por: Shi, Yuhua, et al.
Publicado: (2022)

Mycobacterium tuberculosis PE_PGRS19 Induces Pyroptosis through a Non-Classical Caspase-11/GSDMD Pathway in Macrophages
por: Qian, Jianing, et al.
Publicado: (2022)

Disulfiram attenuates hypoxia-induced pulmonary hypertension by inhibiting GSDMD cleavage and pyroptosis in HPASMCs
por: Hu, Shunlian, et al.
Publicado: (2022)

LDC7559 inhibits microglial activation and GSDMD-dependent pyroptosis after subarachnoid hemorrhage
por: Cai, Wenhua, et al.
Publicado: (2023)

IL-6 Prevents Lung Macrophage Death and Lung Inflammation Injury by Inhibiting GSDME- and GSDMD-Mediated Pyroptosis during Pneumococcal Pneumosepsis
por: Gou, Xuemei, et al.
Publicado: (2022)

Puerarin Inhibits NLRP3-Caspase-1-GSDMD-Mediated Pyroptosis via P2X7 Receptor in Cardiomyocytes and Macrophages
por: Sun, Shuchan, et al.
Publicado: (2023)

Trimetazidine attenuates dexamethasone-induced muscle atrophy via inhibiting NLRP3/GSDMD pathway-mediated pyroptosis
por: Wang, Li, et al.
Publicado: (2021)

Secoisolariciresinol diglucoside induces pyroptosis by activating caspase‐1 to cleave GSDMD in colorectal cancer cells
por: Chen, Tuo, et al.
Publicado: (2022)

Inhibition of GSDMD-mediated pyroptosis triggered by Trichinella spiralis intervention contributes to the alleviation of DSS-induced ulcerative colitis in mice
por: Ma, Zhen-Rong, et al.
Publicado: (2023)

GSDMD-mediated pyroptosis dominantly promotes left ventricular remodeling and dysfunction in post-myocardial infarction: a comparison across modes of programmed cell death and mitochondrial involvement
por: Piamsiri, Chanon, et al.
Publicado: (2023)

ERRα promotes glycolytic metabolism and targets the NLRP3/caspase-1/GSDMD pathway to regulate pyroptosis in endometrial cancer
por: Su, Pingping, et al.
Publicado: (2023)

Ophiopogonin B alleviates cisplatin resistance of lung cancer cells by inducing Caspase-1/GSDMD dependent pyroptosis
por: Cheng, Ziyu, et al.
Publicado: (2022)

Polyphyllin VI Induces Caspase-1-Mediated Pyroptosis via the Induction of ROS/NF-κB/NLRP3/GSDMD Signal Axis in Non-Small Cell Lung Cancer
por: Teng, Jin-Feng, et al.
Publicado: (2020)

Talaromyces marneffei activates the AIM2-caspase-1/-4-GSDMD axis to induce pyroptosis in hepatocytes
por: Wang, Gang, et al.
Publicado: (2022)

Hyperglycemia Aggravates Periodontitis via Autophagy Impairment and ROS-Inflammasome-Mediated Macrophage Pyroptosis
por: Zhao, Zhenxing, et al.
Publicado: (2023)

Hepatic TNFRSF12A promotes bile acid-induced hepatocyte pyroptosis through NFκB/Caspase-1/GSDMD signaling in cholestasis
por: Liao, Min, et al.
Publicado: (2023)

Piceatannol inhibits pyroptosis and suppresses oxLDL-induced lipid storage in macrophages by regulating miR-200a/Nrf2/GSDMD axis
por: Mu, Zhongyuan, et al.
Publicado: (2020)

CircHIPK3 Promotes Pyroptosis in Acinar Cells Through Regulation of the miR-193a-5p/GSDMD Axis
por: Wang, Jiale, et al.
Publicado: (2020)

Peroxiredoxin 3 Inhibits Acetaminophen-Induced Liver Pyroptosis Through the Regulation of Mitochondrial ROS
por: Wang, Yue, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_75nk9nhjkeojgkdc5hqmlkm10i