Epitope-specific airway-resident CD4(+) T cell dynamics during experimental human RSV infection

BACKGROUND: Respiratory syncytial virus (RSV) is an important cause of acute pulmonary disease and one of the last remaining major infections of childhood for which there is no vaccine. CD4(+) T cells play a key role in antiviral immunity, but they have been little studied in the human lung. METHODS...

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Detalles Bibliográficos
Autores principales: Guvenel, Aleks, Jozwik, Agnieszka, Ascough, Stephanie, Ung, Seng Kuong, Paterson, Suzanna, Kalyan, Mohini, Gardener, Zoe, Bergstrom, Emma, Kar, Satwik, Habibi, Maximillian S., Paras, Allan, Zhu, Jie, Park, Mirae, Dhariwal, Jaideep, Almond, Mark, Wong, Ernie H.C., Sykes, Annemarie, Del Rosario, Jerico, Trujillo-Torralbo, Maria-Belen, Mallia, Patrick, Sidney, John, Peters, Bjoern, Kon, Onn Min, Sette, Alessandro, Johnston, Sebastian L., Openshaw, Peter J., Chiu, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2019
Materias:
Clinical Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934186/
https://www.ncbi.nlm.nih.gov/pubmed/31815739
http://dx.doi.org/10.1172/JCI131696

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