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GPR101 mediates the pro-resolving actions of RvD5(n-3 DPA) in arthritis and infections
N-3 docosapentaenoic acid–derived resolvin D5 (RvD5(n-3) (DPA)) is diurnally regulated in peripheral blood and exerts tissue-protective actions during inflammatory arthritis. Here, using an orphan GPCR screening approach coupled with functional readouts, we investigated the receptor(s) involved in m...
Autores principales: | Flak, Magdalena B., Koenis, Duco S., Sobrino, Agua, Smith, James, Pistorius, Kimberly, Palmas, Francesco, Dalli, Jesmond |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934227/ https://www.ncbi.nlm.nih.gov/pubmed/31793912 http://dx.doi.org/10.1172/JCI131609 |
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