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Multiscale, multimodal analysis of tumor heterogeneity in IDH1 mutant vs wild-type diffuse gliomas

Glioma is recognized to be a highly heterogeneous CNS malignancy, whose diverse cellular composition and cellular interactions have not been well characterized. To gain new clinical- and biological-insights into the genetically-bifurcated IDH1 mutant (mt) vs wildtype (wt) forms of glioma, we integra...

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Detalles Bibliográficos
Autores principales: Berens, Michael E., Sood, Anup, Barnholtz-Sloan, Jill S., Graf, John F., Cho, Sanghee, Kim, Seungchan, Kiefer, Jeffrey, Byron, Sara A., Halperin, Rebecca F., Nasser, Sara, Adkins, Jonathan, Cuyugan, Lori, Devine, Karen, Ostrom, Quinn, Couce, Marta, Wolansky, Leo, McDonough, Elizabeth, Schyberg, Shannon, Dinn, Sean, Sloan, Andrew E., Prados, Michael, Phillips, Joanna J., Nelson, Sarah J., Liang, Winnie S., Al-Kofahi, Yousef, Rusu, Mirabela, Zavodszky, Maria I., Ginty, Fiona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934292/
https://www.ncbi.nlm.nih.gov/pubmed/31881020
http://dx.doi.org/10.1371/journal.pone.0219724