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Multiscale, multimodal analysis of tumor heterogeneity in IDH1 mutant vs wild-type diffuse gliomas
Glioma is recognized to be a highly heterogeneous CNS malignancy, whose diverse cellular composition and cellular interactions have not been well characterized. To gain new clinical- and biological-insights into the genetically-bifurcated IDH1 mutant (mt) vs wildtype (wt) forms of glioma, we integra...
Autores principales: | Berens, Michael E., Sood, Anup, Barnholtz-Sloan, Jill S., Graf, John F., Cho, Sanghee, Kim, Seungchan, Kiefer, Jeffrey, Byron, Sara A., Halperin, Rebecca F., Nasser, Sara, Adkins, Jonathan, Cuyugan, Lori, Devine, Karen, Ostrom, Quinn, Couce, Marta, Wolansky, Leo, McDonough, Elizabeth, Schyberg, Shannon, Dinn, Sean, Sloan, Andrew E., Prados, Michael, Phillips, Joanna J., Nelson, Sarah J., Liang, Winnie S., Al-Kofahi, Yousef, Rusu, Mirabela, Zavodszky, Maria I., Ginty, Fiona |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934292/ https://www.ncbi.nlm.nih.gov/pubmed/31881020 http://dx.doi.org/10.1371/journal.pone.0219724 |
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