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Molecular characterization of pulmonary defenses against bacterial invasion in allergic asthma: The role of Foxa2 in regulation of β-defensin 1

Allergic asthma, characterized by chronic airway Th2-dominated inflammation, is associated with an increased risk of infection; however, the underlying mechanisms are unclear. Forkhead box protein A2 (Foxa2) plays a critical role in Th2 inflammation and is associated with pulmonary defenses. To dete...

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Detalles Bibliográficos
Autores principales: Wei, Chuanqi, Tang, Xiaoju, Wang, Faping, Li, Yan, Sun, Lin, Luo, Fengming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934329/
https://www.ncbi.nlm.nih.gov/pubmed/31881038
http://dx.doi.org/10.1371/journal.pone.0226517

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