The Ormdl genes regulate the sphingolipid synthesis pathway to ensure proper myelination and neurologic function in mice

Sphingolipids are membrane and bioactive lipids that are required for many aspects of normal mammalian development and physiology. However, the importance of the regulatory mechanisms that control sphingolipid levels in these processes is not well understood. The mammalian ORMDL proteins (ORMDL1, 2...

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Detalles Bibliográficos
Autores principales: Clarke, Benjamin A, Majumder, Saurav, Zhu, Hongling, Lee, Y Terry, Kono, Mari, Li, Cuiling, Khanna, Caroline, Blain, Hailey, Schwartz, Ronit, Huso, Vienna L, Byrnes, Colleen, Tuymetova, Galina, Dunn, Teresa M, Allende, Maria L, Proia, Richard L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934382/
https://www.ncbi.nlm.nih.gov/pubmed/31880535
http://dx.doi.org/10.7554/eLife.51067

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