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Statistical Analysis of Dual-task Gait Characteristics for Cognitive Score Estimation

Traditional approaches for the screening of cognitive function are often based on paper tests, such as Mini-Mental State Examination (MMSE), that evaluate the degree of cognitive impairment and provide a score of patient’s mental ability. Procedures for conducting paper tests require time investment...

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Autores principales: Matsuura, Taku, Sakashita, Kazuhiro, Grushnikov, Andrey, Okura, Fumio, Mitsugami, Ikuhisa, Yagi, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934525/
https://www.ncbi.nlm.nih.gov/pubmed/31882727
http://dx.doi.org/10.1038/s41598-019-56485-w
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author Matsuura, Taku
Sakashita, Kazuhiro
Grushnikov, Andrey
Okura, Fumio
Mitsugami, Ikuhisa
Yagi, Yasushi
author_facet Matsuura, Taku
Sakashita, Kazuhiro
Grushnikov, Andrey
Okura, Fumio
Mitsugami, Ikuhisa
Yagi, Yasushi
author_sort Matsuura, Taku
collection PubMed
description Traditional approaches for the screening of cognitive function are often based on paper tests, such as Mini-Mental State Examination (MMSE), that evaluate the degree of cognitive impairment and provide a score of patient’s mental ability. Procedures for conducting paper tests require time investment involving a questioner and not suitable to be carried out frequently. Previous studies showed that dementia impaired patients are not capable of multi-tasking efficiently. Based on this observation an automated system utilizing Kinect device for collecting primarily patient’s gait data who carry out locomotion and calculus tasks individually (i.e., single-tasks) and then simultaneously (i.e., dual-task) was introduced. We installed this system in three elderly facilities and collected 10,833 behavior data from 90 subjects. We conducted analyses of the acquired information extracting 12 features of single- and dual-task performance developed a method for automatic dementia score estimation to investigate determined which characteristics are the most important. In result, a machine learning algorithm using single and dual-task performance classified subjects with an MMSE score of 23 or lower with a recall 0.753 and a specificity 0.799. We found the gait characteristics were important features in the score estimation, and referring to both single and dual-task features was effective.
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spelling pubmed-69345252019-12-29 Statistical Analysis of Dual-task Gait Characteristics for Cognitive Score Estimation Matsuura, Taku Sakashita, Kazuhiro Grushnikov, Andrey Okura, Fumio Mitsugami, Ikuhisa Yagi, Yasushi Sci Rep Article Traditional approaches for the screening of cognitive function are often based on paper tests, such as Mini-Mental State Examination (MMSE), that evaluate the degree of cognitive impairment and provide a score of patient’s mental ability. Procedures for conducting paper tests require time investment involving a questioner and not suitable to be carried out frequently. Previous studies showed that dementia impaired patients are not capable of multi-tasking efficiently. Based on this observation an automated system utilizing Kinect device for collecting primarily patient’s gait data who carry out locomotion and calculus tasks individually (i.e., single-tasks) and then simultaneously (i.e., dual-task) was introduced. We installed this system in three elderly facilities and collected 10,833 behavior data from 90 subjects. We conducted analyses of the acquired information extracting 12 features of single- and dual-task performance developed a method for automatic dementia score estimation to investigate determined which characteristics are the most important. In result, a machine learning algorithm using single and dual-task performance classified subjects with an MMSE score of 23 or lower with a recall 0.753 and a specificity 0.799. We found the gait characteristics were important features in the score estimation, and referring to both single and dual-task features was effective. Nature Publishing Group UK 2019-12-27 /pmc/articles/PMC6934525/ /pubmed/31882727 http://dx.doi.org/10.1038/s41598-019-56485-w Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Matsuura, Taku
Sakashita, Kazuhiro
Grushnikov, Andrey
Okura, Fumio
Mitsugami, Ikuhisa
Yagi, Yasushi
Statistical Analysis of Dual-task Gait Characteristics for Cognitive Score Estimation
title Statistical Analysis of Dual-task Gait Characteristics for Cognitive Score Estimation
title_full Statistical Analysis of Dual-task Gait Characteristics for Cognitive Score Estimation
title_fullStr Statistical Analysis of Dual-task Gait Characteristics for Cognitive Score Estimation
title_full_unstemmed Statistical Analysis of Dual-task Gait Characteristics for Cognitive Score Estimation
title_short Statistical Analysis of Dual-task Gait Characteristics for Cognitive Score Estimation
title_sort statistical analysis of dual-task gait characteristics for cognitive score estimation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934525/
https://www.ncbi.nlm.nih.gov/pubmed/31882727
http://dx.doi.org/10.1038/s41598-019-56485-w
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