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mTORC1 and mTORC2 Differentially Regulate Cell Fate Programs to Coordinate Osteoblastic Differentiation in Mesenchymal Stromal Cells

Vascular regeneration depends on intact function of progenitors of vascular smooth muscle cells such as pericytes and their circulating counterparts, mesenchymal stromal cells (MSC). Deregulated MSC differentiation and maladaptive cell fate programs associated with age and metabolic diseases may exa...

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Detalles Bibliográficos
Autores principales: Schaub, Theres, Gürgen, Dennis, Maus, Deborah, Lange, Claudia, Tarabykin, Victor, Dragun, Duska, Hegner, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934532/
https://www.ncbi.nlm.nih.gov/pubmed/31882658
http://dx.doi.org/10.1038/s41598-019-56237-w