Cargando…

Untargeted LC-HRMS-based metabolomics to identify novel biomarkers of metastatic colorectal cancer

Colorectal cancer is one of the main causes of cancer death worldwide, and novel biomarkers are urgently needed for its early diagnosis and treatment. The utilization of metabolomics to identify and quantify metabolites in body fluids may allow the detection of changes in their concentrations that c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Martín-Blázquez, Ariadna, Díaz, Caridad, González-Flores, Encarnación, Franco-Rivas, Daniel, Jiménez-Luna, Cristina, Melguizo, Consolación, Prados, José, Genilloud, Olga, Vicente, Francisca, Caba, Octavio, Pérez del Palacio, José
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934557/ https://www.ncbi.nlm.nih.gov/pubmed/31882610 http://dx.doi.org/10.1038/s41598-019-55952-8

Ejemplares similares

Discovery of Pancreatic Adenocarcinoma Biomarkers by Untargeted Metabolomics
por: Martín-Blázquez, Ariadna, et al.
Publicado: (2020)

Untargeted Metabolomics for the Diagnosis of Exocrine Pancreatic Insufficiency in Chronic Pancreatitis
por: Díaz, Caridad, et al.
Publicado: (2021)

Novel Biomarkers to Distinguish between Type 3c and Type 2 Diabetes Mellitus by Untargeted Metabolomics
por: Jimenez-Luna, Cristina, et al.
Publicado: (2020)

LC-HRMS Metabolomics for Untargeted Diagnostic Screening in Clinical Laboratories: A Feasibility Study
por: Rochat, Bertrand, et al.
Publicado: (2018)

LC-HRMS data as a result of untargeted metabolomic profiling of human cerebrospinal fluid
por: Mehl, Florence, et al.
Publicado: (2018)

Comparison of Three Untargeted Data Processing Workflows for Evaluating LC-HRMS Metabolomics Data
por: Hemmer, Selina, et al.
Publicado: (2020)

An optimized LC-HRMS untargeted metabolomics workflow for multi-matrices investigations in the three-spined stickleback
por: Lebeau-Roche, Emmanuelle, et al.
Publicado: (2021)

Detection of Pork in Beef Meatballs Using LC-HRMS Based Untargeted Metabolomics and Chemometrics for Halal Authentication
por: Windarsih, Anjar, et al.
Publicado: (2022)

Circulating PTGS2, JAG1, GUCY2C and PGF mRNA in Peripheral Blood and Serum as Potential Biomarkers for Patients with Metastatic Colon Cancer
por: Jimenez-Luna, Cristina, et al.
Publicado: (2021)

A novel stable isotope labelling assisted workflow for improved untargeted LC–HRMS based metabolomics research
por: Bueschl, Christoph, et al.
Publicado: (2013)

Scalable Analysis of Untargeted LC-HRMS Data by Means of SQL Database Archiving
por: Mardal, Marie, et al.
Publicado: (2023)

Analysis of Pork in Beef Sausages Using LC-Orbitrap HRMS Untargeted Metabolomics Combined with Chemometrics for Halal Authentication Study
por: Windarsih, Anjar, et al.
Publicado: (2023)

Proteomic biomarkers in body fluids associated with pancreatic cancer
por: Jimenez-Luna, Cristina, et al.
Publicado: (2018)

Towards Standards for Human Fecal Sample Preparation in Targeted and Untargeted LC-HRMS Studies
por: Hosseinkhani, Farideh, et al.
Publicado: (2021)

Development of LC-HRMS Untargeted Analysis Methods for Nasal Epithelial Lining Fluid Exposomics
por: Hsiao, Yun-Chung, et al.
Publicado: (2022)

Automated LC-HRMS(/MS) Approach for the Annotation of Fragment Ions Derived from Stable Isotope Labeling-Assisted Untargeted Metabolomics
por: Neumann, Nora K. N., et al.
Publicado: (2014)

Linking MS1 and MS2 signals in positive and negative modes of LC-HRMS in untargeted metabolomics using the ROIMCR approach
por: Yamamoto, Flávia Yoshie, et al.
Publicado: (2023)

Temozolomide Resistance in Glioblastoma Cell Lines: Implication of MGMT, MMR, P-Glycoprotein and CD133 Expression
por: Perazzoli, Gloria, et al.
Publicado: (2015)

UHPLC-HRMS/MS on untargeted metabolomics: a case study with Copaifera (Fabaceae)
por: Antonio, Ananda da Silva, et al.
Publicado: (2021)

Modulation of MDR1 and MRP3 Gene Expression in Lung Cancer Cells after Paclitaxel and Carboplatin Exposure
por: Melguizo, Consolación, et al.
Publicado: (2012)

Enhanced antitumoral activity of doxorubicin against lung cancer cells using biodegradable poly(butylcyanoacrylate) nanoparticles
por: Melguizo, Consolación, et al.
Publicado: (2015)

Untargeted LC-HRMS Based-Plasma Metabolomics Reveals 3-O-Methyldopa as a New Biomarker of Poor Prognosis in High-Risk Neuroblastoma
por: Barco, Sebastiano, et al.
Publicado: (2022)

Untargeted Metabolic Profiling of 4-Fluoro-Furanylfentanyl and Isobutyrylfentanyl in Mouse Hepatocytes and Urine by Means of LC-HRMS
por: Montesano, Camilla, et al.
Publicado: (2021)

Honey Phenolic Compound Profiling and Authenticity Assessment Using HRMS Targeted and Untargeted Metabolomics
por: Koulis, Georgios A., et al.
Publicado: (2021)

Ammonium Fluoride as Suitable Additive for HILIC-Based LC-HRMS Metabolomics
por: Narduzzi, Luca, et al.
Publicado: (2019)

Addendum: Hemmer, S., et al. Comparison of Three Untargeted Data Processing Workflows for Evaluating LC-HRMS Metabolomics Data. Metabolites 2020, 10, 378
por: Hemmer, Selina, et al.
Publicado: (2020)

Filtering procedures for untargeted LC-MS metabolomics data
por: Schiffman, Courtney, et al.
Publicado: (2019)

Towards Unbiased Evaluation of Ionization Performance in LC-HRMS Metabolomics Method Development
por: Jaeger, Carsten, et al.
Publicado: (2022)

Untargeted Profiling of Tracer-Derived Metabolites Using Stable Isotopic Labeling and Fast Polarity-Switching LC–ESI-HRMS
por: Kluger, Bernhard, et al.
Publicado: (2014)

5-Fluorouracil-loaded poly(ε-caprolactone) nanoparticles combined with phage E gene therapy as a new strategy against colon cancer
por: Ortiz, Raúl, et al.
Publicado: (2012)

QCScreen: a software tool for data quality control in LC-HRMS based metabolomics
por: Simader, Alexandra Maria, et al.
Publicado: (2015)

Comparison of Metabolomic Profiles of Organs in Mice of Different Strains Based on SPME-LC-HRMS
por: Burlikowska, Katarzyna, et al.
Publicado: (2020)

Tracing the metabolism of HT-2 toxin and T-2 toxin in barley by isotope-assisted untargeted screening and quantitative LC-HRMS analysis
por: Meng-Reiterer, Jacqueline, et al.
Publicado: (2015)

Exploratory data fusion of untargeted multimodal LC-HRMS with annotation by LCMS-TOF-ion mobility: White wine case study
por: Mafata, Mpho, et al.
Publicado: (2023)

Untargeted Metabolomics Approach Using UHPLC-HRMS to Unravel the Impact of Fermentation on Color and Phenolic Composition of Rosé Wines
por: Leborgne, Cécile, et al.
Publicado: (2023)

Untargeted Metabolomics Using UHPLC-HRMS Reveals Metabolic Changes of Fresh-Cut Potato during Browning Process
por: Li, Baohong, et al.
Publicado: (2023)

From Samples to Insights into Metabolism: Uncovering Biologically Relevant Information in LC-HRMS Metabolomics Data
por: Ivanisevic, Julijana, et al.
Publicado: (2019)

Human Plasma Metabolomics for Biomarker Discovery: Targeting the Molecular Subtypes in Breast Cancer
por: Díaz-Beltrán, Leticia, et al.
Publicado: (2021)

Untargeted Lipidomic Profiling of Dry Blood Spots Using SFC-HRMS
por: Le Faouder, Pauline, et al.
Publicado: (2021)

3D-MSNet: a point cloud-based deep learning model for untargeted feature detection and quantification in profile LC-HRMS data
por: Wang, Ruimin, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_jd33v3nvpm60dmgqj4a4rivu3g