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Feasibility of improving vascular imaging in the presence of metallic stents using spectral photon counting CT and K-edge imaging

Correct visualization of the vascular lumen is impaired in standard computed tomography (CT) because of blooming artifacts, increase of apparent size, induced by metallic stents and vascular calcifications. Recently, due to the introduction of photon-counting detectors in the X-ray imaging field, a...

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Autores principales: Sigovan, Monica, Si-Mohamed, Salim, Bar-Ness, Daniel, Mitchell, Julia, Langlois, Jean-Baptiste, Coulon, Philippe, Roessl, Ewald, Blevis, Ira, Rokni, Michal, Rioufol, Gilles, Douek, Philippe, Boussel, Loic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934567/
https://www.ncbi.nlm.nih.gov/pubmed/31882698
http://dx.doi.org/10.1038/s41598-019-56427-6
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author Sigovan, Monica
Si-Mohamed, Salim
Bar-Ness, Daniel
Mitchell, Julia
Langlois, Jean-Baptiste
Coulon, Philippe
Roessl, Ewald
Blevis, Ira
Rokni, Michal
Rioufol, Gilles
Douek, Philippe
Boussel, Loic
author_facet Sigovan, Monica
Si-Mohamed, Salim
Bar-Ness, Daniel
Mitchell, Julia
Langlois, Jean-Baptiste
Coulon, Philippe
Roessl, Ewald
Blevis, Ira
Rokni, Michal
Rioufol, Gilles
Douek, Philippe
Boussel, Loic
author_sort Sigovan, Monica
collection PubMed
description Correct visualization of the vascular lumen is impaired in standard computed tomography (CT) because of blooming artifacts, increase of apparent size, induced by metallic stents and vascular calcifications. Recently, due to the introduction of photon-counting detectors in the X-ray imaging field, a new prototype spectral photon-counting CT (SPCCT) based on a modified clinical CT system has been tested in a feasibility study for improving vascular lumen delineation and visualization of coronary stent architecture. Coronary stents of different metal composition were deployed inside plastic tubes containing hydroxyapatite spheres to simulate vascular calcifications and in the abdominal aorta of one New Zealand White (NZW) rabbit. Imaging was performed with an SPCCT prototype, a dual-energy CT system, and a conventional 64-channel CT system (B64). We found the apparent widths of the stents significantly smaller on SPCCT than on the other two systems in vitro (p < 0.01), thus closer to the true size. Consequently, the intra-stent lumen was significantly larger on SPCCT (p < 0.01). In conclusion, owing to the increased spatial resolution of SPCCT, improved lumen visualization and delineation of stent metallic mesh is possible compared to dual-energy and conventional CT.
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spelling pubmed-69345672019-12-29 Feasibility of improving vascular imaging in the presence of metallic stents using spectral photon counting CT and K-edge imaging Sigovan, Monica Si-Mohamed, Salim Bar-Ness, Daniel Mitchell, Julia Langlois, Jean-Baptiste Coulon, Philippe Roessl, Ewald Blevis, Ira Rokni, Michal Rioufol, Gilles Douek, Philippe Boussel, Loic Sci Rep Article Correct visualization of the vascular lumen is impaired in standard computed tomography (CT) because of blooming artifacts, increase of apparent size, induced by metallic stents and vascular calcifications. Recently, due to the introduction of photon-counting detectors in the X-ray imaging field, a new prototype spectral photon-counting CT (SPCCT) based on a modified clinical CT system has been tested in a feasibility study for improving vascular lumen delineation and visualization of coronary stent architecture. Coronary stents of different metal composition were deployed inside plastic tubes containing hydroxyapatite spheres to simulate vascular calcifications and in the abdominal aorta of one New Zealand White (NZW) rabbit. Imaging was performed with an SPCCT prototype, a dual-energy CT system, and a conventional 64-channel CT system (B64). We found the apparent widths of the stents significantly smaller on SPCCT than on the other two systems in vitro (p < 0.01), thus closer to the true size. Consequently, the intra-stent lumen was significantly larger on SPCCT (p < 0.01). In conclusion, owing to the increased spatial resolution of SPCCT, improved lumen visualization and delineation of stent metallic mesh is possible compared to dual-energy and conventional CT. Nature Publishing Group UK 2019-12-27 /pmc/articles/PMC6934567/ /pubmed/31882698 http://dx.doi.org/10.1038/s41598-019-56427-6 Text en © The Author(s) 2019 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Sigovan, Monica
Si-Mohamed, Salim
Bar-Ness, Daniel
Mitchell, Julia
Langlois, Jean-Baptiste
Coulon, Philippe
Roessl, Ewald
Blevis, Ira
Rokni, Michal
Rioufol, Gilles
Douek, Philippe
Boussel, Loic
Feasibility of improving vascular imaging in the presence of metallic stents using spectral photon counting CT and K-edge imaging
title Feasibility of improving vascular imaging in the presence of metallic stents using spectral photon counting CT and K-edge imaging
title_full Feasibility of improving vascular imaging in the presence of metallic stents using spectral photon counting CT and K-edge imaging
title_fullStr Feasibility of improving vascular imaging in the presence of metallic stents using spectral photon counting CT and K-edge imaging
title_full_unstemmed Feasibility of improving vascular imaging in the presence of metallic stents using spectral photon counting CT and K-edge imaging
title_short Feasibility of improving vascular imaging in the presence of metallic stents using spectral photon counting CT and K-edge imaging
title_sort feasibility of improving vascular imaging in the presence of metallic stents using spectral photon counting ct and k-edge imaging
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934567/
https://www.ncbi.nlm.nih.gov/pubmed/31882698
http://dx.doi.org/10.1038/s41598-019-56427-6
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