Distinct role of Sirtuin 1 (SIRT1) and Sirtuin 2 (SIRT2) in inhibiting cargo-loading and release of extracellular vesicles

Exosomes, vehicles for intercellular communication, are formed intracellularly within multivesicular bodies (MVBs) and are released upon fusion with the plasma membrane. For their biogenesis, proper cargo loading to exosomes and vesicle traffic for extracellular release are required. Previously we s...

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Detalles Bibliográficos
Autores principales: Lee, Byung Rho, Sanstrum, Bethany J., Liu, Yutao, Kwon, Sang-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934595/
https://www.ncbi.nlm.nih.gov/pubmed/31882861
http://dx.doi.org/10.1038/s41598-019-56635-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934595/
https://www.ncbi.nlm.nih.gov/pubmed/31882861
http://dx.doi.org/10.1038/s41598-019-56635-0

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