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Histone acetyltransferase and Polo-like kinase 3 inhibitors prevent rat galactose-induced cataract

Diabetic cataracts can occur at an early age, causing visual impairment or blindness. The detailed molecular mechanisms of diabetic cataract formation remain incompletely understood, and there is no well-documented prophylactic agent. Galactose-fed rats and ex vivo treatment of lenses with galactose...

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Detalles Bibliográficos
Autores principales: Kanada, Fumito, Takamura, Yoshihiro, Miyake, Seiji, Kamata, Kazuma, Inami, Mayumi, Inatani, Masaru, Oki, Masaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934598/
https://www.ncbi.nlm.nih.gov/pubmed/31882756
http://dx.doi.org/10.1038/s41598-019-56414-x