Cargando…

Fetal androgen exposure is a determinant of adult male metabolic health

Androgen signalling is a critical driver of male development. Fetal steroid signalling can be dysregulated by a range of environmental insults and clinical conditions. We hypothesised that poor adult male health was partially attributable to aberrant androgen exposure during development. Testosteron...

Descripción completa

Detalles Bibliográficos
Autores principales:	Siemienowicz, Katarzyna J., Filis, Panagiotis, Shaw, Sophie, Douglas, Alex, Thomas, Jennifer, Mulroy, Sally, Howie, Forbes, Fowler, Paul A., Duncan, W. Colin, Rae, Mick T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6934666/ https://www.ncbi.nlm.nih.gov/pubmed/31882954 http://dx.doi.org/10.1038/s41598-019-56790-4

Ejemplares similares

Hepatic Mitochondrial Dysfunction and Risk of Liver Disease in an Ovine Model of “PCOS Males”
por: Siemienowicz, Katarzyna J., et al.
Publicado: (2022)

Early pregnancy maternal progesterone administration alters pituitary and testis function and steroid profile in male fetuses
por: Siemienowicz, Katarzyna J., et al.
Publicado: (2020)

The Pancreas Is Altered by In Utero Androgen Exposure: Implications for Clinical Conditions Such as Polycystic Ovary Syndrome (PCOS)
por: Rae, Mick, et al.
Publicado: (2013)

Disruption of Estrogenic and Androgenic Bioactivities in Human Fetuses Exposed to Maternal Smoking
por: Talia, Chiara, et al.
Publicado: (2021)

In an Ovine Model of Polycystic Ovary Syndrome (PCOS) Prenatal Androgens Suppress Female Fetal Renal Gluconeogenesis
por: Connolly, Fiona, et al.
Publicado: (2015)

Developmental programming of polycystic ovary syndrome (PCOS): prenatal androgens establish pancreatic islet α/β cell ratio and subsequent insulin secretion
por: Ramaswamy, S., et al.
Publicado: (2016)

Nutrient transporter expression in both the placenta and fetal liver are affected by maternal smoking
por: Walker, Natasha, et al.
Publicado: (2019)

Human anogenital distance: an update on fetal smoke-exposure and integration of the perinatal literature on sex differences
por: Fowler, Paul A., et al.
Publicado: (2016)

Insights into Manipulating Postprandial Energy Expenditure to Manage Weight Gain in Polycystic Ovary Syndrome
por: Siemienowicz, Katarzyna, et al.
Publicado: (2020)

Reduced fetal androgen exposure compromises Leydig cell function in adulthood
por: Teerds, Katja J, et al.
Publicado: (2015)

Urinary estrogens as a non-invasive biomarker of viable pregnancy in the giant panda (Ailuropoda melanoleuca)
por: Wilson, Kirsten S., et al.
Publicado: (2019)

Alternative (backdoor) androgen production and masculinization in the human fetus
por: O’Shaughnessy, Peter J., et al.
Publicado: (2019)

The In Utero Programming Effect of Increased Maternal Androgens and a Direct Fetal Intervention on Liver and Metabolic Function in Adult Sheep
por: Hogg, Kirsten, et al.
Publicado: (2011)

The human fetal adrenal produces cortisol but no detectable aldosterone throughout the second trimester
por: Johnston, Zoe C., et al.
Publicado: (2018)

Calretinin is a novel candidate marker for adverse ovarian effects of early life exposure to mixtures of endocrine disruptors in the rat
por: Johansson, Hanna Katarina Lilith, et al.
Publicado: (2020)

Androgen Signaling Disruption during Fetal and Postnatal Development Affects Androgen Receptor and Connexin 43 Expression and Distribution in Adult Boar Prostate
por: Hejmej, Anna, et al.
Publicado: (2013)

Contributions of androgen and estrogen to fetal programming of ovarian dysfunction
por: Abbott, David H, et al.
Publicado: (2006)

Differential Disrupting Effects of Prolonged Low-Dose Exposure to Dichlorodiphenyltrichloroethane on Androgen and Estrogen Production in Males
por: Yaglova, Nataliya V., et al.
Publicado: (2021)

The Role of Androgen in the Adipose Tissue of Males
por: Lee, Hyun-Ki, et al.
Publicado: (2013)

Androgen Treatment in Adolescent Males With Hypogonadism
por: Rey, Rodolfo A., et al.
Publicado: (2020)

The fetal ovary exhibits temporal sensitivity to a ‘real-life’ mixture of environmental chemicals
por: Lea, Richard G., et al.
Publicado: (2016)

Fetal Androgens and Human Sexual Orientation: Searching for the Elusive Link
por: Pasterski, Vickie
Publicado: (2017)

Androgenic potential of human fetal adrenals at the end of the first trimester
por: Savchuk, I, et al.
Publicado: (2017)

Alternative pathway androgen biosynthesis and human fetal female virilization
por: Reisch, Nicole, et al.
Publicado: (2019)

Effects of Fetal Exposure to Asian Sand Dust on Development and Reproduction in Male Offspring
por: Yoshida, Seiichi, et al.
Publicado: (2016)

Circulating androgen regulation by androgen-catabolizing gut bacteria in male mouse gut
por: Hsiao, Tsun-Hsien, et al.
Publicado: (2023)

Expression profile of androgen-modulated microRNAs in the fetal murine lung
por: Bouhaddioui, Wafae, et al.
Publicado: (2016)

Male androgen deficiency: a multisystem syndrome
por: Grossmann, Mathis, et al.
Publicado: (2014)

Cues to Androgens and Quality in Male Gibbon Songs
por: Barelli, Claudia, et al.
Publicado: (2013)

Anabolic androgenic steroid abuse in young males
por: de Ronde, Willem, et al.
Publicado: (2020)

Sensitivity, Specificity and Accuracy of Androgen Deficiency in Ageing Male (ADAM) Questionnaire for the Clinical Detection of Androgen Deficiency in the Male Population in Pakistan
por: Naz, Sidra, et al.
Publicado: (2020)

Modelling foetal exposure to maternal smoking using hepatoblasts from pluripotent stem cells
por: Lucendo-Villarin, Baltasar, et al.
Publicado: (2017)

Androgen and Estrogen Receptor Expression in Different Types of Perianal Gland Tumors in Male Dogs
por: Brodzki, Adam, et al.
Publicado: (2021)

Gene expression profile of androgen modulated genes in the murine fetal developing lung
por: Bresson, Eva, et al.
Publicado: (2010)

Androgen Concentrations in Umbilical Cord Blood and Their Association with Maternal, Fetal and Obstetric Factors
por: Keelan, Jeffrey A., et al.
Publicado: (2012)

Adverse effects of fetal exposure of electronic-cigarettes and high-fat diet on male neonatal hearts
por: Hasan, Kamrul M., et al.
Publicado: (2020)

Influence of Androgens on Circulating Adiponectin in Male and Female Rodents
por: Yarrow, Joshua F., et al.
Publicado: (2012)

Visualising Androgen Receptor Activity in Male and Female Mice
por: Dart, D. Alwyn, et al.
Publicado: (2013)

The influence of maternal androgen excess on the male reproductive axis
por: Holland, Sarah, et al.
Publicado: (2019)

Risk of Central Serous Chorioretinopathy in Male Androgen Abusers
por: Subhi, Yousif, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_iok8jh7c6emtm5gti5srit4mo5